858446-70-5Relevant academic research and scientific papers
Action of tetrabutylammonium tribromide with para-substituted chalcones in protic and aprotic media
Berthelot, Jacques,Benammar,Yamina,Desmazieres, Bernard
, p. 1526 - 1530 (2007/10/03)
Bromination of the double bond of para-substituted chalcones under mild conditions in aprotic solvents is accomplished with high yields using tetrabutylammonium tribromide (TBABr3).In methanol, the main reaction is (α-β) bromoethoxylation.Stereoselectivity, regioselectivity, and chemioselectivity of this bromomethoxylation reaction are described.Key words: bromination, bromoethoxylation, tetrabutylammonium tribromide, (α-β) dibromodihydrochalcones, α-bromo-β-methoxydihydrochalcones.
