132971-99-4

Upstream product

• 22966-19-4 trans-4'-methoxychalcone 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 7145-87-1 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one 
• 7145-87-1 2,3-dibromo-1-(4-methoxyphenyl)-3-phenylpropan-1-one 
• 127-08-2 potassium acetate 
• 64-19-7 acetic acid 
• 141-52-6 sodium ethanolate 
• 64-17-5 ethanol 
• 100-52-7 benzaldehyde 

Downstream Products

• 141855-63-2 4-(4-Methoxy-phenyl)-3-morpholin-4-yl-1,1-dioxo-4,5-dihydro-1H-1λ⁶-isothiazol-4-ol 
• 141855-72-3 4-[4-Chloro-4-(4-methoxy-phenyl)-1,1-dioxo-4,5-dihydro-1H-1λ⁶-isothiazol-3-yl]-morpholine 
• 141855-43-8 N-[2-(4-Methoxy-phenyl)-1-morpholin-4-yl-2-oxo-eth-(Z)-ylidene]-methanesulfonamide 
• 141855-77-8 4-[4-(4-Methoxy-phenyl)-1,1-dioxo-1H-1λ⁶-isothiazol-3-yl]-morpholine 
• 908094-04-2 phenyldiazomethane 
• 3672-52-4 3-(4-methoxyphenyl)-5-phenylisoxazole 
• 24963-15-3 ((2S,3R)-1-Cyclohexyl-3-phenyl-aziridin-2-yl)-(4-methoxy-phenyl)-methanone 
• 141855-30-3 (Z)-1-(4-Methoxy-phenyl)-2-morpholin-4-yl-3-phenyl-propenone 
• 858446-70-5 optically inactive 2-bromo-3-methoxy-1-(4-methoxy-phenyl)-3-phenyl-propan-1-one 

Relevant academic research and scientific papers

Modular access to 1,2-allenyl ketones based on a photoredox-catalysed radical-polar crossover process

Herein, a new protocol dealing with the preparation of 1,2-allenyl ketones has been successfully developedviathe reactions of enynes with radicals enabled by dual photoredox/copper catalysis. Based on the results of a deuteration experiment and the competition reaction between cyclopropanation and allenation, the mechanism based on a photoredox-neutral-catalysed radical-polar crossover process has been proposed. Synthetic applications of allenes have also been demonstrated.

Visible light photoredox catalyzed cascade cyclizations of α-bromochalcones or α-bromocinnamates with heteroarenes

Vinyl radicals were generated from α-bromochalcones or a-bromocinnamate ethyl ester under visible light photoredox catalyzed conditions via an oxidative quenching cycle of the iridium complex [Ir{d(CF 3)ppy}2(dtbbpy)]PF6 and subjected to cascade cyclizations with heteroarenes entailing two consecutive C-C bond formations and three C-H activations. The process is amenable to furans, benzofurans, pyrroles, and indoles, giving rise to a broad variety of novel polycyclic frameworks in high yields under mild and environmentally benign reaction conditions.