85872-53-3

Usage

Uses

Used in Pharmaceutical Industry:
1,3-DIPROPYL-8-PHENYLXANTHINE is used as a selective A1 adenosine antagonist for its potential therapeutic applications in various conditions. Its ability to block the A1 adenosine receptor can lead to the modulation of physiological processes, making it a candidate for the development of drugs targeting specific diseases.
Additionally, 1,3-Dialkyl-8-(p-sulfophenyl)xanthines, which are related compounds, are potent water-soluble antagonists for both A1 and A2 adenosine receptors. This class of compounds can be used in the development of drugs with broader antagonistic activity, potentially offering more versatile therapeutic options in the treatment of various conditions.

InChI:InChI=1/C17H20N4O2/c1-3-10-20-15-13(16(22)21(11-4-2)17(20)23)18-14(19-15)12-8-6-5-7-9-12/h5-9H,3-4,10-11H2,1-2H3,(H,18,19)

Upstream product

• 100-52-7 benzaldehyde 
• 81250-33-1 1,3-di-n-propyl-5-nitroso-6-aminouracil 
• 41862-14-0 6-amino-1,3-dipropyluracil 
• 81250-34-2 1,3-dipropyl-5,6-diaminouracil 
• 127252-57-7 6-Amino-5-{[1-phenyl-meth-(E)-ylidene]-amino}-1,3-dipropyl-1H-pyrimidine-2,4-dione 
• 94781-75-6 6-amino-5-banzamido-1,3-dipropyluracil 
• 127252-57-7 6-Amino-5-{[1-phenyl-meth-(E)-ylidene]-amino}-1,3-dipropyl-1H-pyrimidine-2,4-dione 

Downstream Products

• 120362-49-4 7-methyl-1,3-dipropyl-8-phenylxanthine 

Relevant academic research and scientific papers

Xanthines, optionally incorporated in liposomes, for promoting skin or hair pigmentation

A method of treating skin or hair for promoting pigmentation wherein a xanthine component, in an amount effective to promote pigmentation, is incorporated in liposomes or hydrated lipidic lamellar phases.

1,3,8-Trisubstituted xanthines. Effect of substitution pattern upon adenosine receptor A1/A2 affinity

A series of 11,8-substituted xanthines having three different substitution patterns on the 1- and 3-positions was prepared.These compounds were assessed for

A NEW AND FACILE SYNTHESIS OF 8-ARYLXANTHINES

The treatment of 6-amino-5-benzylideneaminouracil derivatives with iodine gave the corresponding xanthines in high yields.

Xanthine derivatives

Novel 8-phenylxanthines which are potent adenosine receptor antagonists.

1,3-Dialkyl-8-(p-sulfophenyl)xanthines: Potent Water-Soluble Antagonistst for A1- and A2-Adenosine Receptors

A series of 8-(substituted phenyl) derivatives of Theophylline and other 1,3-dialkylxanthines were evaluated for potency and selectivity as antagonists at A1- and A2-adenosine receptors in brain tissue.Theophylline has a similar pote