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860649-42-9

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860649-42-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 860649-42-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,0,6,4 and 9 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 860649-42:
(8*8)+(7*6)+(6*0)+(5*6)+(4*4)+(3*9)+(2*4)+(1*2)=189
189 % 10 = 9
So 860649-42-9 is a valid CAS Registry Number.

860649-42-9Relevant articles and documents

Preparation method of antitumor drug gemcitabine hydrochloride

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Paragraph 0045; 0049-0051, (2020/12/31)

The invention discloses a preparation method of an antitumor drug gemcitabine hydrochloride. The preparation method specifically comprises the following processes: (1) preparing an antitumor drug gemcitabine hydrochloride intermediate: Step 1, synthesis of T1; Step2, synthesis of T2; Step3, synthesis of T3; Step4, synthesis of T4; Step5, synthesis of T5; and Step6, synthesis of T6; and (2) preparing gemcitabine hydrochloride from the gemcitabine hydrochloride intermediate: Step7, firstly reducing T6 with lithium tri (tert-butoxy) aluminum hydride, and then acylating with paratoluensulfonyl chloride to prepare T7, wherein T7 is 2-deoxy-2, 2-difluoro-D-ribofuranose-3, 5-dibenzoate; and Step8, reacting T7 with cytosine under the action of a catalyst to generate T8, wherein T8 is 2'-deoxy-2',2'-difluorocytidine-D-ribofuranose-3',5'-dibenzoate. The preparation method of the antitumor drug gemcitabine hydrochloride has the advantages of low production cost, favorability for industrial production and small environmental pollution.

Novel sterol/stanol phosphorylnitroderivatives and use thereof in treating or preventing cardiovascular disease, its underlying conditions and other disorders

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Page/Page column 11, (2008/06/13)

Sterol and stanol phosphorylnitro derivatives and their use in treating or preventing cardiovascular disease, its underlying conditions and other disorders are disclosed. The disclosed compounds include a phosphate linker, at least one moiety that releases nitric oxide (NO), and a sterol or stanol moiety. Some compounds additionally include an ascorbyl moiety to make the compound more readily soluble in aqueous and non-aqueous media.

Novel derivatives of androstane and androstene with ascorbic acid and use thereof in treating or preventing various conditions, diseases, and disorders

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Page 9, (2008/06/13)

The present invention provides novel derivatives comprising compounds in the androstane and androstene series, coupled with ascorbic acid, including salts thereof, and represented by one or more of the general formulae: wherein R1, R2, R3, R4, R5, R6 may individually be chosen from hydrogen, OH, carbonyl, and an ascorbyl moiety; and R7 may be hydrogen or any halogen.

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