861151-22-6Relevant articles and documents
Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB1 receptor antagonists
Lange, Jos H.M.,van der Neut, Martina A.W.,den Hartog, Arnold P.,Wals, Henri C.,Hoogendoorn, Jan,van Stuivenberg, Herman H.,van Vliet, Bernard J.,Kruse, Chris G.
experimental part, p. 1752 - 1757 (2010/07/08)
The synthesis, structure-activity relationship (SAR) studies and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles are described. The target compounds 6-18 represent a novel class of potent and selective CB1 r
1,3,5-trisubstituted 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity
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Page/Page column 6-7, (2010/02/13)
The present invention relates to 1,3,5-trisubstituted 4,5-dihydro-1H-pyrazole derivatives as CB1 antagonists, to methods for the preparation of these compounds and to novel intermediates useful for the synthesis of said pyrazole derivatives. Th