86310-45-4

Basic information

• Product Name: bis(2-phenylethyl)propanedioic acid
• CAS NO: 86310-45-4
• Molecular Formula: C₁₉H₂₀O₄
• Molecular Weight: 312.3597
• Mol File: 86310-45-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 482.9°C at 760 mmHg
• Flash Point: 259.9°C
• Density: 1.225g/cm³
• Vapor Pressure: 3.9E-10mmHg at 25°C
• Refractive Index: 1.594
• CAS DataBase Reference: bis(2-phenylethyl)propanedioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: bis(2-phenylethyl)propanedioic acid(86310-45-4)
• EPA Substance Registry System: bis(2-phenylethyl)propanedioic acid(86310-45-4)

Safety Data

• Hazardous Substances Data: 86310-45-4(Hazardous Substances Data)

Upstream product

• 34887-18-8 diethyl 2,2-diphenethylmalonate 
• 103-63-9 1-phenyl-2-bromoethane 
• 123-51-3 i-Amyl alcohol 
• 105-53-3 diethyl malonate 

Downstream Products

• 17486-92-9 2-(2-phenylethyl)-3,4-dihydro-2H-naphthalen-1-one 
• 62115-21-3 2-phenethyl-4-phenyl-butyric acid amide 
• 855222-57-0 2-phenethyl-4-phenyl-butyric acid-(2-diethylamino-ethyl ester) 
• 855215-89-3 2-phenethyl-4-phenyl-butyryl chloride 
• 145600-21-1 2,2'-bis(2-phenylethyl)-N,N'-bis(8-quinolyl)malonamide 
• 861330-79-2 diphenethyl-malonyl chloride 
• 17486-91-8 2-(2-phenylethyl)-4-phenylbutanoic acid 

Relevant articles and documents

CARBOXYLIC DERIVATIVES FOR USE IN THE TREATMENT OF CANCER

The invention provides novel compounds of formula (I), wherein: R1 is a radical derived from one of the known ring systems; R2 is a phenyl radical optionally substituted; Xn represents a birradical selected from the group consisting of: -(CH2)1-4-, (C2-C4)-alkenyl, (C2-C4)alkynyl, -S-(CH2)1-3-#, and -(CH2)1-3-O-#; wherein the symbol # indicates the position at which Xn is attached to R1; Yn is a birradical selected from the group consisting of: -(CH2)2-4-, -S-(CH2)1-3#, and -O-(CH2)1-3-#,; where in the symbol # indicates the position at which Yn is attached to R2; and R3 is a radical selected from the group consisting of: -OR4. The compounds of formula (I) are useful in the treatment of cancer

Dipeptides as renin inhibitors

Dipeptides are described which are represented by the formula STR1 wherein the various substituents are defined hereinbelow. These compounds have a strong inhibitory efect on human renin, and are useful as a therapeutically active agent for the treatment of hypertension, especially renin-associated hypertension.