6076-32-0

Upstream product

• 10585-86-1 1,2-Di-O-isopropyliden-3-O-octadecyl-sn-glycerin 
• 86334-56-7 1-octadecyloxy-3-trityloxy-propan-2-ol 
• 31081-59-1 1-octadecyl methanesulfonate 
• 112-92-5 1-octadecanol 
• 83537-01-3 (-)-1-O-octadecyl-2-O-acetyl-sn-glycerol 
• 80707-96-6 Ro 15-4454 
• 83526-57-2 (S)-1-(benzyloxy)-3-(octadecyloxy)propan-2-ol 
• 3386-32-1 n-octadecyl p-toluenesulfonate 
• 132280-81-0 1-(octadecyloxy)-3-(trityloxy)propan-2-one 
• 83526-60-7 2-O-Acetyl-1-O-benzyl-3-O-octadecyl-sn-glycerin 
• 83526-54-9 3-O-Octadecyl-1-O-p-toluolsulfonyl-sn-glycerin 
• 83526-53-8 (R)-1,2-Epoxy-3-(octadecyloxy)propan 

Downstream Products

• 80707-92-2 2-O-Benzyl-3-O-octadecyl-1-O-trityl-sn-glycerin 
• 129170-94-1 3-((R)-1-Octadecyloxymethyl-2-trityloxy-ethoxy)-isoxazole 
• 83526-51-6 3-O-Octadecyl-2-O-p-toluolsulfonyl-3-O-trityl-sn-glycerin 
• 83526-61-8 2-O-Methyl-3-O-octadecyl-1-O-trityl-sn-glycerin 
• 129170-95-2 3-((S)-1-Octadecyloxymethyl-2-trityloxy-ethoxy)-isoxazole 
• 96022-72-9 2-O-Benzyl-3-O-octadecyl-1-O-<2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-β-D-glucopyranosyl>-rac-glycerin 
• 80459-30-9 2-O-Benzyl-1-O-octadecyl-3-O-trityl-sn-glycerin 
• 83526-59-4 2-O-Acetyl-3-O-benzyl-1-O-octadecyl-sn-glycerin 
• 83526-52-7 3-O-Octadecyl-2-O-p-toluolsulfonyl-sn-glycerin 
• 83526-55-0 (R)-1-O-octadecyl-3-(p-toluenesulfonyl)-glycerol 
• 83526-75-4 (S)-1-O-octadecyl-3-acetylglycerol 
• 83526-72-1 3-O-Acetyl-1-O-octadecyl-sn-glycerin 
• 83537-02-4 3-O-Benzyl-2-O-formyl-1-O-octadecyl-sn-glycerin 
• 83526-74-3 1-O-Acetyl-2-O-benzyl-3-O-octadecyl-sn-glycerin 

Relevant academic research and scientific papers

D and L etherlipid stereoisomers and liposomes

A liposome having a lipid bilayer, where the lipid bilayer includes either the L or D stereoisomer of an ether lipid or a non-equal mixture of both. Most preferably the liposome also comprises (a) an underivatized phosphatidylcholine; (b) a sterol; (c) about 5-20 mole % of a phosphatidylethanolamine linked to a dicarboxylic acid at the ethanolamine group of the phosphatidylethanolamine, and (d) greater than about 10 mole % to less than about 30 mole % of either the L or D stereoisomer of an ether lipid. The liposome may be used as an anti-cancer or anti-inflammatory agent.

Synthesis of glyceryl ethers in high optical purity via ruthenium catalyzed asymmetric hydrogenation

1-O-octadecyl-3-O-trityl-glycerol and 1-O-benzyl-3-O-trityl-glycerol can be prepared by asymmetric catalytic hydrogenation in O.P.> 96% and 87-88% respectively.

Stereoselective Synthesis of Long-chain 1-O-(β-D-Maltosyl)-3-O-alkyl-sn-glycerols (Alkyl Glyceryl Ether Lysoglycolipids)

The synthesis of long-chain 2-O-benzyl-3-O-alkyl-sn-glycerols 5 was improved, making these compounds easily accessible for glycosylation experiments.Glycosylation with α-acetobromomaltose following a modified Koenings-Knorr procedure after removal of the protective groups yielded the title compound 9 in good yields.These compounds represent examples of alkyl glyceryl ether lysoglycolipids.Some properties of these amphiphilic compounds with a nonionic carbohydrate head-group differ not much (critical micell concentration, hemolytic activity), other properties differ very much (antitumor efficiency) from the properties of the analogous compounds with a zwitterionic phosphorylcholine head-group.