86395-59-7

Upstream product

• 2109-92-4 2-(4-Chlor-benzyl)-1-methoxy-propan-2-ol 
• 637-87-6 1-Chloro-4-iodobenzene 
• 513-42-8 3-hydroxy-2-methyl-1-propene 
• 1745-18-2 1-allyl-4-chlorobenzene 
• 64-18-6 formic acid 

Downstream Products

• 2109-30-0 1-Carbamoyloxy-2-carbamoyloxymethyl-2-<4-chlor-benzyl>-propan 
• 2109-29-7 2-<4-Chlor-benzyl>-2-hydroxymethyl-propan-1-ol 

Relevant academic research and scientific papers

Carbonylative Transformation of Allylarenes with CO Surrogates: Tunable Synthesis of 4-Arylbutanoic Acids, 2-Arylbutanoic Acids, and 4-Arylbutanals

In this Communication, procedures for the selective synthesis of 4-arylbutanoic acids, 2-arylbutanoic acids, and 4-arylbutanals from the same allylbenzenes have been developed. With formic acid or TFBen as the CO surrogate, reactions proceed selectively and effectively under carbon monoxide gas-free conditions.

Palladium-catalyzed arylation of allylic alcohols with aryl iodides in water

Palladium-catalyzed arylation of allylic alcohols with aryl iodides are shown to occur in the presence of sodium bicarbonate and tetra-n-butylammonium chloride in pure water using palladium acetate as catalyst. β-aromatic carbonyl compounds are obtained in good yields.