86770-00-5

Upstream product

• 610-97-9 o-iodo-methyl-benzoic acid 
• 100-42-5 styrene 
• 63104-88-1 Methyl 2-styrylbenzoate 
• 204847-93-8 trans-stilbene-2-carbonyl chloride 
• 62-53-3 aniline 
• 5079-90-3 (E)-2-styrylbenzoic acid 

Downstream Products

• 21868-93-9 2,3-Diphenyl-3,4-dihydro-isocarbostyril 
• 4679-90-7 3-benzyl-N-phenyl isoindolin-1-one 
• 82971-75-3 (E)-3-benzylidene-N-phenylisoindolin-1-one 

Relevant academic research and scientific papers

An Easy-to-Machine Electrochemical Flow Microreactor: Efficient Synthesis of Isoindolinone and Flow Functionalization

Flow electrochemistry is an efficient methodology to generate radical intermediates. An electrochemical flow microreactor has been designed and manufactured to improve the efficiency of electrochemical flow reactions. With this device only little or no supporting electrolytes are needed, making processes less costly and enabling easier purification. This is demonstrated by the facile synthesis of amidyl radicals used in intramolecular hydroaminations to produce isoindolinones. The combination with inline mass spectrometry facilitates a much easier combination of chemical steps in a single flow process.

Intramolecular Hydroamidation of ortho-Vinyl Benzamides Promoted by Potassium tert-Butoxide/N,N-Dimethylformamide

An intramolecular hydroamidation of ortho-vinyl benzamides had been developed. The reaction was promoted efficiently by potassium tert-butoxide and N,N-dimethylformamide without the need for strong oxidants or transition-metal catalysts. A series of dihyd