86847-63-4 Usage
Uses
Used in Pharmaceutical Research:
2,2-DIMETHYL-N-(3-TRIMETHYLSILANYL-PYRIDIN-2-YL)-PROPIONAMIDE is used as a research compound for exploring its potential pharmacological properties and applications in the development of new drugs and therapeutic agents. Its unique structure and functional groups make it a promising candidate for various medicinal chemistry studies.
Used in Organic Synthesis:
In the field of organic synthesis, 2,2-DIMETHYL-N-(3-TRIMETHYLSILANYL-PYRIDIN-2-YL)-PROPIONAMIDE serves as a key intermediate or building block for the synthesis of more complex organic molecules. Its versatile chemical properties allow it to be used in various synthetic routes and reactions, contributing to the advancement of organic chemistry.
Used in Disease Treatment:
2,2-DIMETHYL-N-(3-TRIMETHYLSILANYL-PYRIDIN-2-YL)-PROPIONAMIDE has been studied for its potential use in the treatment of various diseases and conditions. Its pharmacological properties and interactions with biological targets make it a candidate for further research and development as a therapeutic agent.
Check Digit Verification of cas no
The CAS Registry Mumber 86847-63-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,8,4 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 86847-63:
(7*8)+(6*6)+(5*8)+(4*4)+(3*7)+(2*6)+(1*3)=184
184 % 10 = 4
So 86847-63-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H22N2OSi/c1-13(2,3)12(16)15-11-10(17(4,5)6)8-7-9-14-11/h7-9H,1-6H3,(H,14,15,16)
86847-63-4Relevant academic research and scientific papers
Regiospecific Electrophilic Substitution of Aminopyridines: Ortho Lithiation of 2-, 3-, and 4-(Pivaloylamino)pyridines
Turner, James A.
, p. 3401 - 3408 (2007/10/02)
2- and 4-(pivaloylamino)pyridines have been shown to undergo metalation exclusively at C-3 and these smoothly react with a variety of electrophiles to produce 2,3- and 3,4-disubstituted pyridines, respectively.Removal of the pivaloyl protecting group results in overall electrophilic substitution of an aminopyridine.Utilization of this method is exemplified by efficient syntheses of 2- and 4-aminonicotinaldehydes.Minor modifications of the reaction conditions permitted exclusive ortho metalation of 2-(pivaloylamino)pyridines additionally functionalized by chloro, fluoro, or methyl groups.Although the major product from reaction of 3-(pivaloylamino)pyridine by this method was metalation at C-4, the reaction was complicated by substantial quantities of product derived from nucleophilic attack by n-butyllithium on the pyridine nucleus.
