86847-83-8

Basic information

• Product Name: N-(5-Chloro-pyridin-2-yl)-2,2-dimethylpropanamide
• Synonyms: N-(5-Chloro-pyridin-2-yl)-2,2-dimethylpropanamide
• CAS NO: 86847-83-8
• Molecular Formula: C₁₀H₁₃ClN₂O
• Molecular Weight: 213
• Mol File: 86847-83-8.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(5-Chloro-pyridin-2-yl)-2,2-dimethylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-Chloro-pyridin-2-yl)-2,2-dimethylpropanamide(86847-83-8)
• EPA Substance Registry System: N-(5-Chloro-pyridin-2-yl)-2,2-dimethylpropanamide(86847-83-8)

Safety Data

• Hazardous Substances Data: 86847-83-8(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 86847-59-8 2-(pivaloylamino)pyridine 
• 121953-45-5 (1-Benzotriazol-1-yl-2,2-dimethyl-propyl)-(5-chloro-pyridin-2-yl)-amine 
• 1072-98-6 5-chloro-2-pyridylamine 

Downstream Products

• 705291-49-2 2-(tert-butylcarbonylamino)-5-chloronicotinic acid 

Relevant articles and documents

Chlorination Reaction of Aromatic Compounds and Unsaturated Carbon-Carbon Bonds with Chlorine on Demand

Chlorination with chlorine is straightforward, highly reactive, and versatile, but it has significant limitations. In this Letter, we introduce a protocol that could combine the efficiency of electrochemical transformation and the high reactivity of chlorine. By utilizing Cl3CCN as the chloride source, donating up to all three chloride atom, the reaction could generate and consume the chlorine in situ on demand to achieve the chlorination of aromatic compounds and electrodeficient alkenes.

METHODS AND COMPOSITIONS FOR INHIBITION OF BROMODOMAIN-CONTAINING PROTEINS

The present invention relates to compounds that bind to and otherwise modulate the activity of bromodomain-containing proteins, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders.

5, 7-DIHYDRO- 6H-PYRIMIDO [ 5, 4-D] [ 1 ] BENZAZEPIN-6-THIONES AS PLK INHIBITORS

This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.