869470-04-2

Upstream product

• 52771-14-9 2-acetamido-2-(4-methoxyphenyl) acetic acid 
• 77629-84-6 (±)-ethyl 2-azido-2-(4-methoxyphenyl)acetate 
• 148000-82-2 2-acetamido-2-(4'-methoxyphenyl)acetate d'ethyle 
• 77629-83-5 ethyl 2-bromo-2-(4-methoxyphenyl) acetate 
• 14062-18-1 ethyl p-methoxyphenylacetate 
• 77648-21-6 ethyl 2-amino-2-(4-methoxyphenyl) acetate 

Relevant academic research and scientific papers

Diastereochemical diversity of imidazoline scaffolds via substrate controlled TMSCI mediated cycloaddition of azlactones

(Chemical Equation Presented) We report herein a trimethylsilyl chloride mediated substrate controlled 1,3-dipolar cycloaddition for the diastereoselective synthesis of either syn- or anti-imidazolines. This method provides scaffolds with four points of diversity and control over two stereocenters.