86971-43-9

Upstream product

• 622-97-9 1-ethenyl-4-methylbenzene 
• 1146-44-7 4,4'-dichlorophenyl thiosulfonate 
• 1866-39-3 trans-p-methylcinnamic acid 
• 7559-36-6 4-methyl-β-nitrostyrene 
• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 2751-25-9 p-chlorophenylsulfonyl hydrazide 
• 3405-89-8 2-(4-chloro-phenylsulfonyl)acetic acid 
• 104-87-0 4-methyl-benzaldehyde 
• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 766-97-2 4-n-methylphenylacetylene 

Downstream Products

• 86432-77-1 C₁₆H₁₅ClO₂S 

Relevant academic research and scientific papers

A Study of Graphene-Based Copper Catalysts: Copper(I) Nanoplatelets for Batch and Continuous-Flow Applications

The use of graphene derivatives as supports improves the properties of heterogeneous catalysts, with graphene oxide (GO) being the most frequently employed. To explore greener possibilities as well as to get some insights into the role of the different gr

Synthesis of Vinyl Sulfones via I2-mediated Alkene Sulfonylations with Thiosulfonates

A simple sulfonylation strategy involving I2 and thiosulfonates, as sulfonyl-group precursors, is reported for the synthesis of vinyl sulfones. Sulfonyl radicals are presumed to be generated from thiosulfonates, which subsequently react with st

Mn(III)-mediated regioselective synthesis of (: E)-vinyl sulfones from sodium sulfinates and nitro-olefins

An efficient Mn(iii)-mediated coupling reaction of sodium sulfinates with nitro-olefins has been developed, this reaction proceeds in mild and open-flask conditions to afford (E)-vinyl sulfones with high regioselectivities and in good to excellent yields. The control experiments revealed that this transformation could involve a radical process.

Silver-Catalyzed Denitrative Sulfonylation of β-Nitrostyrenes: A Convenient Approach to (E)-Vinyl Sulfones

The first utilization of β-nitrostyrenes (readily available by the Henry reaction) for a highly stereoselective, convenient, and catalytic synthesis of (E)-vinyl sulfones at room temperature was investigated. The protocol involves efficient silver-catalyz

Revealing the metal-like behavior of iodine: An iodide-catalysed radical oxidative alkenylation

In this work, we have described an alternative alkenylation approach to illustrate the metal-like behaviour of iodine in cross-coupling reactions. Alkenylation could proceed through iodide catalysed radical initiation, radical addition and iodine promoted

(E)-4-carboxystyrl-4-chlorobenzyl sulfone and pharmaceutical compositions thereof

Pre-treatment with α,β unsaturated aryl sulfones protects normal cells from the cytotoxic side effects of two classes of anticancer chemotherapeutics. Administration of a cytoprotective sulfone compound to a patient prior to anticancer chemotherapy with a

Styryl sulfone anticancer agents

Styryl sulfone compounds of the invention selectively inhibit proliferation of tumor cells, and induce apoptosis of tumor cells, while sparing normal cells. The compounds, which are useful in the treatment of cancer and other proliferative disorders, have

Styryl sulfone anticancer agents

Styryl sulfone compounds of the invention selectively inhibit proliferation of tumor cells, and induce apoptosis of tumor cells, while sparing normal cells. The compounds, which are useful in the treatment of cancer and other proliferative disorders, have

Reactions of Arenesulfonyl Chlorides with Olefins Catalyzed by a Ruthenium(II) Complex

Arenesulfonyl chlorides react with vinylarenes in the presence of dichlorotris(triphenylphosphine)ruthenium(II) catalyst and 1 molar equiv of a tertiary amine to form α,β-unsaturated sulfones 2.Only the E isomers of the sulfones are formed.In reactions of arenesulfonyl chlorides containing an electron-withdrawing Cl or NO2 substituent with α-methylstyrenes, 2-aryl-3-(arylsulfonyl)propenes (5) are also formed.Mechanisms for these reactions are proposed.