87040-40-2

Basic information

• Product Name: (+/-)-N-methylpseudoephedrine
• Synonyms: (+/-)-N-methylpseudoephedrine
• CAS NO: 87040-40-2
• Molecular Weight: 179.262
• Mol File: 87040-40-2.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: (+/-)-N-methylpseudoephedrine(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-N-methylpseudoephedrine(87040-40-2)
• EPA Substance Registry System: (+/-)-N-methylpseudoephedrine(87040-40-2)

Safety Data

• Hazardous Substances Data: 87040-40-2(Hazardous Substances Data)

Upstream product

• 15351-09-4 metamfepramone 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 93-55-0 1-phenyl-propan-1-one 
• 6084-17-9 2-chloro-1-phenylpropan-1-one 
• 299-42-3 (R,R)-(-)-pseudoephedrine 
• 67-68-5 dimethyl sulfoxide 
• 50-00-0 formaldehyd 
• 26251-08-1 2-nitro-1-phenylpropan-1-ol 
• 492-39-7 (1S,2S)-2-amino-1-phenylpropanol 
• 130459-53-9 (1R,2S)-2-(tert-butoxycarbonyl(methyl)amino)-1-phenyl-1-propanol 
• 90-82-4 pseudoephedrine 
• 74-88-4 methyl iodide 
• 16251-47-1 (4S,5S)-3,4-dimethyl-5-phenyl-1,3-oxazolidin-2-one 
• 66574-19-4 (4S,5S)-3,4-dimethyl-5-phenyl-1,3-oxazolidine 

Downstream Products

• 158837-63-9 (1S,2S)-1-Phenyl-1-phthalimido-2-(dimethylamino)propane 
• 129216-60-0 lithium N-methylpseudoephedrate 
• 14222-20-9 1R,2R-N-methylpseudoephedrine 
• 445298-99-7 (S,S)-N-methylpseudoephedrine α-bromo-α-n-butylacetate 
• 479350-68-0 (S,S)-N-methylpseudoephedrine 2-bromo-4-phenylbutanoate 
• 1078720-31-6 (1S,2S)-N-(2-hydroxy-1-methyl-2-phenylethyl)-N,N-dimethyl-hexadecan-1-ammonium bromide 
• 1041013-28-8 (1S,2S)-2-(dimethylamino)-1-phenylpropyl 3-[(4-fluorobenzoyl)amino]-6,6-dimethyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate 
• 1017295-11-2 (R(p))-1,2-ferrocenediyl(BMe(OMe))(SnMe₂Cl) 
• 67-63-0 isopropyl alcohol 

Relevant articles and documents

Enantioselective and Diastereoselective Construction of Chiral Amino Alcohols by Iridium-f-Amphox-Catalyzed Asymmetric Hydrogenation via Dynamic Kinetic Resolution

The iridium-f-amphox-catalyzed asymmetric hydrogenation of racemic α-amino β-unfunctionalized ketones proceeds via a DKR (dynamic kinetic resolution) process for the construction of various chiral N,N-disubstituted α-amino β-unfunctionalized alcohols in quantitative yields with excellent enantioselectivities and diastereoselectivities (all products >99% ee and >99:1 dr, TON up to 100 000). Importantly, this catalytic asymmetric hydrogenation with a DKR process provided a highly efficient and powerful synthetic strategy for the preparation of key chiral intermediates of the preclinical antitumor agent (S,S)-R116010.

1,2-Aminothioethers Derived from Ephedrine and Pseudoephedrine: Heterobidentate Ligands for the Palladium-Catalysed Asymmetric Allylic Substitution Reaction

Heterobidentate sulfide-tertiary amine ligands incorporating 1,2-aminothioethers derived from ephedrine and pseudoephedrine have been prepared and used successfully in the palladium-catalysed asymmetric allylic substitution reaction, giving ees of up to 89 percent. The stereoelectronic effects operating in the reactions are discussed.

Facile inversion of configuration of N-Boc-β-aminoalcohols via S(N)2 cyclization to oxazolidinones

Oxazolidinones are obtained by the cyclization of mesylates derived from N-Boc-β-Aminoalcohols. Hydrolysis of the N-Boc-Oxazolidinones regenerates the protected aminoalcohols with inverted configuration at the hydroxy group. (C) 2000 Elsevier Science Ltd.