872059-44-4

Upstream product

• 100-51-6 benzyl alcohol 
• 849831-52-3 3-(3-bromophenyl)-2-methylpropionic acid 

Downstream Products

• 881206-91-3 (S)-benzyl 1-(3-acetylphenyl)propan-2-ylcarbamate 
• 946088-72-8 C₁₉H₂₃NO₃ 
• 946088-73-9 Benzyl (S)-1-(3-((R)-1-hydroxyethyl)phenyl)propan-2-ylcarbamate 
• 1057086-31-3 benzyl (S)-1-(3-((S)-1-azidoethyl)phenyl)propan-2-ylcarbamate 
• 881207-02-9 Benzyl (S)-1-(3-((R)-1-aminoethyl)phenyl)propan-2-ylcarbamate 
• 1057086-30-2 benzyl (S)-1-(3-((S)-1-aminoethyl)phenyl)propan-2-ylcarbamate 
• 913722-72-2 benzyl (S)-1-(3-((S)-1-N-Boc-aminoethyl)phenyl)propan-2-ylcarbamate 
• 946088-74-0 C₁₉H₂₂N₂O₃ 
• 946088-61-5 C₃₁H₃₁N₂O₃P 
• 1057253-68-5 (S)-benzyl 1-(3-(2-hydroxypropan-2-yl)phenyl)propan-2-ylcarbamate 
• 1057253-65-2 (S)-benzyl 1-(3-(2-azidopropan-2-yl)phenyl)propan-2-ylcarbamate 
• 894791-74-3 (S)-1-(3-(2-Aminopropan-2-yl)phenyl)propan-2-amine 
• 881209-04-7 tert-Butyl (S)-1-(3-((S)-2-aminopropyl)phenyl)ethylcarbamate 
• 872059-43-3 [2-(3-chlorosulfonyl-phenyl)-1S-methyl-ethyl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Comparative approaches toward diamines containing spatially separated homobenzylic and benzylic nitrogen stereocenters

Several synthetic strategies to diamines 1-3 are described. The optimum approach via opening of aziridine afforded 1-3 in 29-60% yield over 3-5 steps. A study on formation of the benzylic stereocenter using Toste's rhenium-catalyzed asymmetric reduction of phosphinyl ketimines was also evaluated and afforded 15 in 92% de.