881206-91-3

Basic information

• Product Name: Carbamic acid, [(1S)-2-(3-acetylphenyl)-1-methylethyl]-, phenylmethyl ester
• CAS NO: 881206-91-3
• Molecular Formula: C19H21NO3
• Molecular Weight: 311.381
• Mol File: 881206-91-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S)-2-(3-acetylphenyl)-1-methylethyl]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S)-2-(3-acetylphenyl)-1-methylethyl]-, phenylmethyl ester(881206-91-3)
• EPA Substance Registry System: Carbamic acid, [(1S)-2-(3-acetylphenyl)-1-methylethyl]-, phenylmethyl ester(881206-91-3)

Safety Data

• Hazardous Substances Data: 881206-91-3(Hazardous Substances Data)

Upstream product

• 872059-44-4 [2-(3-bromo-phenyl)-1S-methyl-ethyl]-carbamic acid benzyl ester 
• 100-51-6 benzyl alcohol 
• 501-53-1 benzyl chloroformate 
• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 6429-44-3 (S)-(-)-N-(benzyloxycarbonyl)alaninol 
• 39172-32-2 2-(3-bromophenyl)-2-methyl-[1,3]dioxolane 
• 849831-52-3 3-(3-bromophenyl)-2-methylpropionic acid 
• 946088-68-2 benzyl 2-methylaziridine-1-carboxylate 
• 107484-93-5 C₁₀H₁₁BrMgO₂ 
• 111-34-2 -butyl vinyl ether 

Downstream Products

• 946088-72-8 C₁₉H₂₃NO₃ 
• 946088-73-9 Benzyl (S)-1-(3-((R)-1-hydroxyethyl)phenyl)propan-2-ylcarbamate 
• 946088-74-0 C₁₉H₂₂N₂O₃ 
• 1057253-68-5 (S)-benzyl 1-(3-(2-hydroxypropan-2-yl)phenyl)propan-2-ylcarbamate 
• 1057086-31-3 benzyl (S)-1-(3-((S)-1-azidoethyl)phenyl)propan-2-ylcarbamate 
• 881207-02-9 Benzyl (S)-1-(3-((R)-1-aminoethyl)phenyl)propan-2-ylcarbamate 
• 1057086-30-2 benzyl (S)-1-(3-((S)-1-aminoethyl)phenyl)propan-2-ylcarbamate 
• 913722-72-2 benzyl (S)-1-(3-((S)-1-N-Boc-aminoethyl)phenyl)propan-2-ylcarbamate 
• 946088-61-5 C₃₁H₃₁N₂O₃P 
• 1057253-65-2 (S)-benzyl 1-(3-(2-azidopropan-2-yl)phenyl)propan-2-ylcarbamate 
• 894791-74-3 (S)-1-(3-(2-Aminopropan-2-yl)phenyl)propan-2-amine 
• 881209-04-7 tert-Butyl (S)-1-(3-((S)-2-aminopropyl)phenyl)ethylcarbamate 

Relevant articles and documents

Comparative approaches toward diamines containing spatially separated homobenzylic and benzylic nitrogen stereocenters

Several synthetic strategies to diamines 1-3 are described. The optimum approach via opening of aziridine afforded 1-3 in 29-60% yield over 3-5 steps. A study on formation of the benzylic stereocenter using Toste's rhenium-catalyzed asymmetric reduction of phosphinyl ketimines was also evaluated and afforded 15 in 92% de.

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The present invention relates to compounds having the general structure: and pharmaceutically acceptable salts and hydrates thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myelo