913722-72-2Relevant academic research and scientific papers
Comparative approaches toward diamines containing spatially separated homobenzylic and benzylic nitrogen stereocenters
Achmatowicz, Michal,Chan, Johann,Wheeler, Philip,Liu, Longbin,Faul, Margaret M.
, p. 4825 - 4829 (2008/02/05)
Several synthetic strategies to diamines 1-3 are described. The optimum approach via opening of aziridine afforded 1-3 in 29-60% yield over 3-5 steps. A study on formation of the benzylic stereocenter using Toste's rhenium-catalyzed asymmetric reduction of phosphinyl ketimines was also evaluated and afforded 15 in 92% de.
SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE
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Page/Page column 46, (2008/06/13)
The present invention relates to compounds having the general structure: (I) and pharmaceutically acceptable salts and hydrates thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple m
Substituted heterocyclic compounds and methods of use
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Page/Page column 19, (2008/06/13)
The present invention relates to compounds having the general structure: and pharmaceutically acceptable salts and hydrates thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myelo
