87259-92-5Relevant articles and documents
Design and implementation of an efficient synthetic approach to furanosylated indolocarbazoles: Total synthesis of (+)- and (-)-K252a
Wood, John L.,Stoltz, Brian M.,Dietrich, Hans-Jürgen,Pflum, Derek A.,Petsch, Dejah T.
, p. 9641 - 9651 (2007/10/03)
The first total synthesis of the natural product (+)-K252a (2) has been achieved in 12 steps from commercially available materials, with a longest linear sequence of seven steps and an overall yield of 21%. The synthetic strategy employs novel rhodium carbenoid chemistry in the construction of both the indolocarbazole aglycon (4) and the carbohydrate moiety (9).
Synthesis of the Indolocarbazole Natural Products Staurosporinone and Arcyriaflavin B
Hughes, Ian,Nolan, William P.,Raphael, Ralph A.
, p. 2475 - 2480 (2007/10/02)
Flexible synthetic routes involving double nitrene insertions are described leading to the indolocarbazole systems present in a growing group of natural products.The methods are exemplified by the total synthesis of two members of this group stauro