40899-99-8

Usage

Uses

2,2''-Biindolyl is a useful reagent for the preparation of indolo[2,3-a]carbazole.

InChI:InChI=1/C16H12N2/c1-3-7-13-11(5-1)9-15(17-13)16-10-12-6-2-4-8-14(12)18-16/h1-10,17-18H

Upstream product

• 1484-27-1 3-bromoindole 
• 98192-27-9 5,6,5',6'-tetrahydroxy-2,2'-biindolyl 
• 172950-81-1 1-acetyl-2,3-dihydro-2,2'-bisindole 
• 529-28-2 4-iodoanisol 
• 171021-33-3 2,2,2-trifluoro-N-(2-(4-[2,2,2-trifluoro-acetylamino-phenyl]-buta-1,3-diynyl)-phenyl)-acetamide 
• 29540-83-8 p-tolyl triflate 
• 99-90-1 para-bromoacetophenone 
• 52670-38-9 2-ethynylaniline 

Downstream Products

• 170707-32-1 6-N-(dimethoxybenzyl)-staurosporinone 
• 244634-56-8 C₃₀H₂₅N₃O₃ 
• 544409-16-7 4-(1H,1'H-[2,2']biindolyl-3-yl)-1,5-dihydro-pyrrol-2-one 

Relevant academic research and scientific papers

Synthesis of 3,3′-disubstituted-2,2′-biindolyls through sequential palladium-catalysed reactions of 2,2,2-trifluoro-N-(2-(4-[2,2,2- trifluoro-acetylamino)-phenyl]-buta-1,3-diynyl)-phenyl)-acetamide with organic halides/triflates

Palladium-catalysed reactions of aryl iodides/vinyl triflates with 2,2,2-trifluoro-N-(2-(4-[2,2,2-trifluoro-acetylamino)-phenyl]-buta-1,3-diynyl) -phenyl)-acetamide provide a straightforward entry into 3,3′- disubstituted-2,2′-biindolyls. Subsequent appli

[Cp*IrCl2]2 catalyzed formation of 2,2′-biindoles from 2-ethynylanilines

[Cp*IrCl2]2 catalyzes the cyclization of 2-ethynylanilines to 2,2′-biindoles via intramolecular hydroamination. A reaction pathway has been proposed on the basis of deuterium labeling experiments and computational studies.

Reduction of indigo: Simple syntheses of 3-acetoxy-, 1-acetyl-2.3-dihydro-, 3-acetoxy-3′-acetyl-, 3-acetoxy-1,3′-diacetyl-2,2′-bisindoles, and 2,2′-bisindole

Indigo was converted to 2,2′-bisindole by the direct reduction with zinc in acetic acid and acetic anhydride under argon or hydrogen atmosphere. Reduction with tin and iron afforded 3-acetoxy-2,2′-bisindole predominantly. Useful building blocks such as 1-acetyl-2,3-dihydro-, 3-acetoxy-3′-acetyl-, and 3-acetoxy-1,3′-diacetyl-2,2′-bisindoles were also produced depending on metal and reaction conditions.

2,2'-Biindolyl revisited. Synthesis and reactions

An improved synthesis of 2,2'-biindolyl (1) is described. Derivatives of 1 with a variety of substituents in the 3,3'-positions, such as the 3,3'-diformyl derivative 19 have been synthesized. Potential syntheses of indolocarbazole alkaloids from such deri

SYNTHESIS AND SPECTROSCOPIC CHARACTERISTICS OF 2,3'-BIINDOLYLS AND 2,2'-INDOLYLPYRROLES

A general and selective method has been achieved to synthesize 2,3'-biindolyls and 2,2'-indolylpyrroles through an acid catalyzed reaction of 3-bromoindoles with indoles or pyrroles.I.R., (1)H-NMR, (13)C-NMR and MS data of the dimers are also reported.