87548-97-8

Usage

InChI:InChI=1/C14H10OS/c1-9-5-4-7-11-13(15)10-6-2-3-8-12(10)16-14(9)11/h2-8H,1H3

Upstream product

• 87548-96-7 2-(2'-Methylphenylthio)benzoic acid 
• 147-93-3 Thiosalicylic acid 
• 108-88-3 toluene 
• 95-46-5 2-methylphenyl bromide 
• 137-06-4 2-thiocresol 
• 118-91-2 ortho-chlorobenzoic acid 

Downstream Products

• 152810-97-4 N-(4-Methyl-9H-thioxanthen-9-yl) benzyl carbamate 

Relevant academic research and scientific papers

Photobase generator

The object of the present invention is to provide a photobase generator capable of efficiently generating amines (tertiary amines and amidine) high in catalytic activity by sensing light with a wavelength of from 350 to 500 nm (especially, from 400 to 500 nm). The present invention is a photobase generator characterized in being represented by general formula (1) or (2). Y+ is a quaternary ammonio group of general formula (3) to (5), and X? is a counter anion selected from among a borate anion, a phenolate anion, and a carboxylate anion.

Synthesis of N-(9H-xanthen-9-yl)aminoalkanamide and N-(9H-thioxanthen-9-yl)aminoalkanamide derivatives and their in vitro evaluation as potential intercalators and antitumor drugs

A series of new N-(9H-xanthen-9-yl)aminoalkanamide and N-(9H-thioxanthen-9-yl)aminoalkanamide derivatives was synthesized and evaluated as potential intercalators by measuring their DNA binding affinity. They were also tested for cytotoxic activity against L1210. The results suggest that the cytotoxicity of these molecules was not due to an intercalating mechanism.

Synthesis and antitumor activity of some new 2-chloroethylnitrosoureas

The synthesis of a series of N-(2-chloroethyl)-N'-(9H-xanthen-9-yl)-N-nitrosoureas and N-(2-chloroethyl)-N'-(9H-thioxanthen-9-yl)-N-nitrosoureas is described. The title compounds were evaluated against NSCLCN6 L16 bronchial epidermoid carcinoma in vitro and some of them were found to be active. N-(2-chloroethyl)-N'-(2-methoxy-9H-xanthen-9-yl)-N-nitrosourea (8e) was active against leukemia P388 tumor system in mice.

Methyl substituted thioxanthones and thioxanthone-10,10-dioxides

The preparation of all four monomethylthioxanthones and their corresponding dioxides is described.A previously published synthesis of the 2- and 3-methylthioxanthones by Gilman and Diehl has been shown to produce the 2- and 4-methyl isomers.