877614-77-2

Upstream product

• 83863-40-5 4-phenyl-1-(p-tolylsulfonyl)piperidin-4-ol 
• 98-59-9 p-toluenesulfonyl chloride 
• 762-72-1 allyl-trimethyl-silane 
• 70-55-3 toluene-4-sulfonamide 
• 78388-19-9 4-methyl-N-(3-methylbut-2-enyl)benzenesulfonamide 
• 30057-92-2 N-(p-toluenesulfonyl)aminoacetophenone 
• 18303-04-3 N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide 
• 2219-56-9 2-phenyl-2,3-butadien-1-ol 
• 1334217-86-5 N-(2-phenylbuta-2,3-dienyl)-4-tolylsulfonamide 
• 3360-54-1 3-bromo-2-phenylprop-1-ene 
• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 
• 117794-75-9 N-allyl-N-[2-(phenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide 
• 33439-27-9 N-tosyl-4-piperidone 
• 80213-12-3 1-[(4-methylbenzene)-sulfonyl]-4-piperidinol 

Downstream Products

• 897625-49-9 4-phenyl-1-(toluene-4-sulfonyl)-pyrrolidin-3-one 

Relevant academic research and scientific papers

Expanding the Protecting Group Scope for the Carbonyl Olefin Metathesis Approach to 2,5-Dihydropyrroles

Chiral pyrrolidine derivatives are important building blocks for natural product synthesis. Carbonyl olefin metathesis has recently emerged as a powerful tool for the construction of such building blocks from chiral amino acid derivatives. Here, we demons

AuCl3-Catalyzed Ring-Closing Carbonyl–Olefin Metathesis

Compared with the ripeness of olefin metathesis, exploration of the construction of carbon–carbon double bonds through the catalytic carbonyl–olefin metathesis reaction remains stagnant and has received scant attention. Herein, a highly efficient AuCl3-catalyzed intramolecular ring-closing carbonyl–olefin metathesis reaction is described. This method features easily accessible starting materials, simple operation, good functional-group tolerance and short reaction times, and provides the target cyclopentenes, polycycles, benzocarbocycles, and N-heterocycle derivatives in good to excellent yields.

Carbonyl-Olefin Metathesis Catalyzed by Molecular Iodine

The carbonyl-olefin metathesis reaction could facilitate rapid functional group interconversion and allow construction of complicated organic structures. Herein, we demonstrate that elemental iodine, a very simple catalyst, can efficiently promote this chemical transformation under mild reaction conditions. Our mechanistic studies revealed intriguing aspects of the activation mode via molecular iodine and the iodonium ion that could change the previously established perception of catalyst and substrate design for the carbonyl-olefin metathesis reaction.

Iodonium-Catalyzed Carbonyl-Olefin Metathesis Reactions

The carbonyl-olefin metathesis reaction has become increasingly important in organic synthesis due to its versatility in functional group interconversion chemistry. Recent developments in the field have identified a number of transition-metal and organic Lewis acids as effective catalysts for this reaction. Herein, we report the use of simple organic compounds such as N-iodosuccinimide or iodine monochloride to catalyze the carbonyl-olefin metathesis process under mild reaction conditions. This work broadens the scope of this chemical transformation to include iodonium sources as simple and practical catalysts.

A metal complex compound ligand, metal complex and its preparation method and application, high molecular polymer and its preparation method and application

The invention discloses a metal complex ligand, a metal complex, a preparation method and application thereof. Structural formulas of the metal (M) complex ligand Ia-Ic and the metal complex IIa-IIc thereof are shown in the description. The metal complex

FeCl3-Catalyzed Ring-Closing Carbonyl–Olefin Metathesis

Exploiting catalytic carbonyl–olefin metathesis is an ongoing challenge in organic synthesis. Reported herein is an FeCl3-catalyzed ring-closing carbonyl–olefin metathesis. The protocol allows access to a range of carbo-/heterocyclic alkenes wi

Silver-catalyzed intramolecular aminofluorination of activated allenes

A nice combination: The intramolecular oxidative aminofluorination of allenes using silver catalysis and FN(SO2Ph)2 as the fluorinating reagent has been developed. This reaction represents an efficient method for the synthesis of various 4-fluoro-2,5-dihydropyrrole compounds. Further transformation provided the corresponding fluorinated pyrrole derivatives in good yields (see scheme).

HIGHLY ACTIVE METATHESIS CATALYSTS SELECTIVE FOR ROMP AND RCM REACTIONS

The present invention relates to a kind of novel carbene ligands and corresponding new ruthenium catalysts, which are highly active and selective for ROMP and RCM reactions. It discloses the significant electronic effect of different substituted carbene l

Highly flexible synthesis of chiral azacycles via iridium-catalyzed hydrogenation

A range of saturated chiral azacycles has been prepared in high yield and with high selectivity from simple starting materials. A modular approach with ring-closing metathesis as a key step was used to produce a number of five-, six-, and seven-membered c

RUTHENIUM COMPLEX LIGAND, RUTHENIUM COMPLEX, CARRIED RUTHENIUM COMPLEX CATALYST AND THE PREPARING METHODS AND THE USE THEREOF

The present invention disclosed a kind of ruthenium complex ligands, ruthenium complexes and immobilized ruthenium complex catalysts. The invention also relates to preparation and use of new ruthenium complex ligands, ruthenium complexes and immobilized ruthenium complex catalysts. The ruthenium complex ligand I and ruthenium complex II in the present invention have the following structures: The immobilized ruthenium complex catalysts in the present invention have the structure of IV: In the present invention, the ruthenium complexes and immobilized ruthenium complex catalysts have several significant advantages, e.g., high catalytic activity, high stability, easy recovery and reusability.