87797-61-3Relevant academic research and scientific papers
A method for the synthesis of quinoline derivatives
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Paragraph 0067-0070, (2017/08/23)
The invention belongs to the technical field of organic synthesis and particularly relates to a synthesis method of quinoline derivatives. The synthesis method comprises the steps of sequentially adding aromatic amine, aldehyde and alcohol into a reaction
A method for utilizing the aromatic amine, aromatic aldehyde, synthesized of quinoline derivatives
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Paragraph 0036; 0037, (2018/01/11)
The invention provides a method for synthesizing a quinoline derivative by utilizing arylamine, aromatic aldehyde and ketone, and belongs to the technical field of the synthesis of the quinoline derivative. According to the method for synthesizing a quinoline derivative by utilizing arylamine, aromatic aldehyde and ketone, in the existence of silver trifluoromethanesulfonate and trifluoromethanesulfonic acid, the quinoline derivative is synthesized by virtue of the reaction of an arylamine compound, an aromatic aldehyde compound and ketone compound. A reaction general formula is as shown in the specification. Compared with the prior art, the method is not only applicable to a great amount of functional groups, but also is simple in operation, high in yield, single in product structure, convenient to separate and purify, safe, low in price and small in pollution.
Palladium-Catalyzed [5+1] Annulation of 2-(1-Arylvinyl) Anilines and α-Diazocarbonyl Compounds toward Multi-functionalized Quinolines
Zhu, Jiawei,Hu, Weiming,Sun, Song,Yu, Jin-Tao,Cheng, Jiang
, p. 3725 - 3728 (2017/09/25)
A palladium-catalyzed [5+1] annulation of 2-(1-arylvinyl) anilines and α-diazocarbonyl compounds has been developed, affording a series of multi-functionalized quinolines in moderate to good yields. This procedure proceeded with the sequential insertion o
Method for constructing quinoline compound by means of functionalization of organic antimony catalyzed C-H bond
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Paragraph 0092; 0093, (2017/08/29)
The invention aims at developing a novel method for preparing a quinoline compound in a manner of high conversion rate and high yield from organic antimony frustrated lewis pair catalyst by means of C-H bond functionalization of imine and unsaturated hydr
Silver-catalyzed one-step synthesis of multiply substituted quinolines
Xu, Xuefeng,Liu, Wenmin,Wang, Zhiqiang,Feng, Yuquan,Yan, Yanlei,Zhang, Xu
supporting information, p. 226 - 229 (2015/12/31)
A silver-catalyzed formation of C-C bond for the construction of a series of polysubstituted quinolines from arylamines, aldehydes, and ketones or arylamines and 1,3-diketones has been developed. The transformation is effective for a broad range of substrates, thus enabling the expansion of constituent architectures on the heterocyclic framework. This use of a single catalytic system to mediate chemical transformations in a synthetic operation is important for the development of new atom-economic strategies and this strategy is efficient in building complex structures from simple starting materials in an environmentally benign fashion.
Silver-catalyzed three-component approach to quinolines starting from anilines, aldehydes, and alcohols
Zhang, Xu,Liu, Wenmin,Sun, Ruixue,Xu, Xuefeng,Wang, Zhiqiang,Yan, Yanlei
, p. 1563 - 1568 (2016/06/14)
A silver-catalyzed sequential formation of two C-C bonds for the construction of a series of polysubstituted quinolines from anilines, aldehydes, and alcohols under mild conditions has been developed. The transformation is effective for a broad range of substrates, including aliphatic alcohols, arylalkanols, cycloalkanols, and ethylene glycol, thereby permitting the expansion of the constituent architectures of the heterocyclic framework.
Organic reactions in water: A distinct approach for the synthesis of quinoline derivatives starting directly from nitroarenes
Das, Biswanath,Jangili, Paramesh,Kashanna, Jajula,Kumar, Rathod Aravind
experimental part, p. 3267 - 3270 (2011/11/30)
Three-component reactions of nitroarenes, aldehydes, and phenylacetylene in the presence of indium in dilute hydrochloric acid produce the corresponding quinoline derivatives under reflux. The conversion in this one-pot synthesis involves the following steps: (i) reduction of the nitroarenes to anilines, (ii) coupling of the anilines, aldehydes, and phenylacetylene, (iii) cyclization of the resulting species, and (iv) dehydrogenation of the cyclic intermediates. Several new quinolines have been prepared. Georg Thieme Verlag Stuttgart · New York.
THE REACTION OF IMIDOYL RADICALS WITH MULTIPLE CARBON-CARBON BONDS
Leardini, Rino,Nanni, Daniele,Tundo, Antonio,Zanardi, Giuseppe
, p. 637 - 642 (2007/10/02)
A general view on the reaction between imidoyl radicals and carbon-carbon double or triple bonds is given; the synthesis of substituted quinolines starting from imines and alkenes is described, pointing out the differences with respect to the analogous reaction performed with alkynes.
Aromatic Annelation by Reaction of Arylimidoyl Radicals with Alkynes: Evidence for the Intervention of a Spirocyclohexadienyl Radical in the Synthesis of Substituted Quinolines
Leardini, Rino,Nanni, Daniele,Pedulli, Gian Franco,Tundo, Antonio,Zanardi, Giuseppe
, p. 1591 - 1594 (2007/10/02)
Arylimidoyl radicals, generated by hydrogen abstraction from N-arylideneanilines with di-isopropyl peroxydicarbonate, react with alkynes to give quinolines in good yields.The reaction also involves an intermediate spirocyclohexadienyl radical; the proposed mechanism is discussed.
1H and 13C NMR spectral studies of some 2,4-diphenylquinoline derivatives
Osborne, A. G.
, p. 477 - 486 (2007/10/02)
The 400 MHz 1H and 14 MHz 13C NMR spectra of a series of 2,4-diphenylquinoline derivatives are presented.The characteristic H-3 and ipso-phenyl carbon signals are the most useful for the identification of these compounds.The effects of a peri-phenyl/methy
