879088-40-1

Basic information

• Product Name: 2-(2-chloro-5-nitrophenyl)pyridine
• Synonyms: 2-(2-chloro-5-nitrophenyl)pyridine;4-Chloro-3-(pyridin-2-yl)nitrobenzene;2-(2-chloro-5-nitrophenyl)pyridine hydrochloride
• CAS NO: 879088-40-1
• Molecular Formula: C₁₁H₇ClN₂O₂
• Molecular Weight: 235
• Mol File: 879088-40-1.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-(2-chloro-5-nitrophenyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chloro-5-nitrophenyl)pyridine(879088-40-1)
• EPA Substance Registry System: 2-(2-chloro-5-nitrophenyl)pyridine(879088-40-1)

Safety Data

• Hazardous Substances Data: 879088-40-1(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 879088-40-1 differently. You can refer to the following data:
1. 2-(2-Chloro-5-nitrophenyl)pyridine is used in the synthesis of Vismondegib (V674700) a hedgehog pathway inhibitor.
2. 2-(2-Chloro-5-nitrophenyl)pyridine is used in the synthesis of Vismondegib (V674700) a hedgehog pathway inhibitor

Upstream product

• 74534-15-9 1-chloro-2-iodo-4-nitrobenzene 
• 4253-79-6 2-(3-nitrophenyl)pyridine 
• 110-86-1 pyridine 
• 694-59-7 pyridine N-oxide 
• 645-00-1 m-iodonitrobenzene 
• 103985-13-3 2-(3-nitrophenyl)pyridine 1-oxide 
• 81745-83-7 pyridin-2-ylzinc(ll) bromide 
• 23082-50-0 2'-chloro-5'-nitroacetophenone 
• 109-76-2 Trimethylenediamine 
• 675-20-7 piperidin-2-one 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 4381-32-2 2-(2-chlorophenyl)pyridine 
• 694-80-4 2-bromo-1-chlorobenzene 
• 14925-39-4 2-bromoacrolein 

Downstream Products

• 879085-55-9 vismodegib 
• 879088-41-2 4-chloro-3-(pyridin-2-yl)benzeneamine 

Relevant articles and documents

Preparation method of vimodegil

The invention provides a preparation method of vimodegil. 2-chloro-5-nitroacetophenone is used as a raw material; 5-oxo-5-(2-chloro-5-nitrophenyl) n-valeraldehyde is prepared through an addition reaction between 2-chloro-5-nitroacetophenone and acrolein,

A [...] synthesis of intermediates method and application

The invention relates to a method for synthesizing intermediate [...] and application, which belongs to the field of organic synthesis, in particular to intermediate 2 - (2 - chloro - 5 - nitrophenyl) pyridine (i.e. compound A) preparation process, compri

Preparation method of vismodegib

The invention relates to a preparation method of vismodegib. The preparation method of the vismodegib comprises the following steps: taking 2-chlorine-5-nitroacetophenone as a starting material, performing 1,4-addition reaction on the 2-chlorine-5-nitroac