88-11-9

Basic information

• Product Name: Diethylthiocarbamoyl chloride
• Synonyms: N,N-DIETHYLCARBAMOTHIOIC CHLORIDE;DIETHYLTHIOCARBAMOYL CHLORIDE;Diethylthiocarbamoyl chloride, tech;dlethylthiocarbamyl chloride;NSC 379476;Diethylcarbamothioic chloride, Diethylthiocarbamoyl chloride;Diethylcarbamothioyl chloride, tech;DiethylthiocarbaMoyl chloride 95%
• CAS NO: 88-11-9
• Molecular Formula: C₅H₁₀ClNS
• Molecular Weight: 151.66
• EINECS: 201-799-0
• Product Categories: Miscellaneous Reagents;Organic Building Blocks;Sulfur Compounds;Thiocarbonyl Compounds
• Mol File: 88-11-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 45-50 °C(lit.)
• Boiling Point: 113 °C10 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /solid
• Density: 1.119 (estimate)
• Vapor Pressure: 0.00105mmHg at 25°C
• Refractive Index: 1.6100 (estimate)
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• PKA: 0.30±0.50(Predicted)
• Stability: Hygroscopic, Water Sensitive
• CAS DataBase Reference: Diethylthiocarbamoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: Diethylthiocarbamoyl chloride(88-11-9)
• EPA Substance Registry System: Diethylthiocarbamoyl chloride(88-11-9)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34
• Safety Statements: 22-26-27-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 88-11-9(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Crystalline Solid

Uses

Different sources of media describe the Uses of 88-11-9 differently. You can refer to the following data:
1. Diethylthiocarbamoyl chloride (N,N′-Diethylthiocarbamoyl chloride) may be used in the following syntheses:aryl isothiocyanates5-substituted 4-methyl-2-thiazolyl diethyldithiocarbamatesnovel type of vasorelaxant hybrid compounds
2. Diethylthiocarbamoyl chloride is a useful synthetic intermediate

General Description

Diethylthiocarbamoyl chloride is a thiocarbamoyl derivative. It has been reported to participate in the thionation of amides as thionating reagent.

InChI:InChI=1/C5H10ClNS/c1-3-7(4-2)5(6)8/h3-4H2,1-2H3

Upstream product

• 97-77-8 disulfiram 
• 463-71-8 thiophosgene 
• 109-89-7 diethylamine 
• 137-26-8 Thiram 

Downstream Products

• 77502-58-0 4-methyl-piperazine-1-carbothioic acid diethylamide 
• 112866-80-5 diethyl-thiocarbamic acid O-(4-benzyl-phenyl ester) 
• 101784-08-1 diethyl-thiocarbamic acid O-(2-benzyl-4-chloro-phenyl ester) 
• 112866-79-2 diethyl-thiocarbamic acid O-(2-benzyl-phenyl ester) 
• 95-05-6 tetraethylthiuram monosulfide 
• 95-30-7 benzo[d]thiazol-2-yl diethylcarbamodithioate 
• 21198-48-1 4,4-diethyl-thiosemicarbazide 
• 70646-94-5 3-(2-Benzoyl-4-chloro-phenyl)-1,1-diethyl-thiourea 
• 37419-79-7 3,3-diethyl-3',3'-dimethyl-1,1'-[4-(4-nitro-phenyl)-[1,2,4]dithiazolidine-3,5-diylidene]-bis-thiourea 
• 17467-76-4 N_.N-Diethylthiocarbamidsaeure-S-(2.4-dinitrophenyl)ester 
• 39707-28-3 Diethyl-thiocarbamic acid O-cyclohex-2-enyl ester 
• 36586-99-9 3-[4-(4-Chloro-phenylamino)-phenyl]-1,1-diethyl-thiourea 
• 36587-02-7 1,1-Diethyl-3-[4-(4-nitro-phenylamino)-phenyl]-thiourea 
• 17467-80-0 N_.N-Diethylthiocarbamidsaeure-S-(2-chlor-4.6-dinitro-phenylester) 

Relevant articles and documents

Synthesis of Carbamic Esters Derivatives of Itols: Antifungal Activity against Various Crop Diseases

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Method for preparing substituted thiophenol and heterocyclic thiophenol by continuous flow reactor

The invention relates to a method for preparing substituted thiophenol and heterocyclic thiophenol by a continuous flow reactor. Phenol and phenol derivatives or heterocyclic phenol are taken as starting materials, and target compounds are prepared by four-step reactions of chlorination, esterification, rearrangement and hydrolysis, wherein the rearrangement reaction is conducted in the continuousflow reactor. According to the method, the reaction is guaranteed by a miniaturized heating device for high-temperature reaction and heat generated by the reaction, the conversion rate and the yieldhigher than those in the conventional reactor are obtained in the short residence time of tens of seconds, relevant side reactions are reduced, meanwhile, fluctuation of temperature and concentrationis avoided in the reaction process, temperature run-away and overheat are avoided, and the reaction process is safe and controllable.

SYNTHESIS OF N,N-DIALKYLCHLOROTHIOFORMAMIDES AND THEIR REACTIONS WITH PHOSPHOROUS ACID ESTERS

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