88292-45-9

Upstream product

• 917-64-6 methyl magnesium iodide 
• 88002-15-7 Phenylglyoxylsaeure-<(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)-1-cyclohexyl>ester 
• 65253-04-5 (-)-8-phenylmenthol 
• 10487-92-0 d,l-O-Acetylatrolactinsaeure 
• 88292-41-5 2-Oxopropansaeure-<(1R,2S,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl>ester 
• 75-16-1 methylmagnesium bromide 
• 676-58-4 methylmagnesium chloride 

Downstream Products

• 138291-09-5 8-Phenylmenthyl (S)-2-phenylpropionate 
• 138291-10-8 (-)-8-Phenylmenthyl (R)-2-phenylpropionate 
• 1123-85-9 (+)-(R)-2-phenylpropanol 
• 37778-99-7 (S)-2-phenyl-1-propanol 
• 2406-22-6 (R)-1-phenyl-1,2-ethanediol 

Relevant academic research and scientific papers

Asymmetric syntheses with a new optically active perhydronaphthalene based chiral auxiliary

(1R,4aS,8S,8aS)-8-(5'-Methoxy-2'-methylphenyl)-8-methyldecahydro-1-nap hthalenol 3a is a highly efficient chiral auxiliary in the Diels-Alder addition of its acrylate ester 5 and in the DIBAL-H and Grignard reactions of its phenylglyoxylate ester 7.

Stereogenic Reactions of the α-Carbon Radicals of 8-Phenylmenthyl Esters

The stereoselective free-radical type reduction and cyclisation of 8-phenylmenthyl esters is described; the predominant products are considered to be derived from the transition states with conformations having the larger substituent anti to the alkoxy group of the ester.

Asymmetric Induction. Reduction, Nucleophilic Addition to, and Ene Reactions of Chiral α-Ketoesters

Ketoesters of 8-phenylmenthol undergo reduction with potassium tri-isopropoxyborohydride, addition of Grignard reagents, and ene reactions with asymmetric induction levels of 90percent and above.