88326-51-6

Basic information

• Product Name: cyclopent-3-ene-1,1-dicarboxylic acid
• Synonyms: cyclopent-3-ene-1,1-dicarboxylic acid;3-Cyclopentene-1,1-dicarboxylic acid
• CAS NO: 88326-51-6
• Molecular Formula: C₇H₈O₄
• Molecular Weight: 156.14
• EINECS: -0
• Mol File: 88326-51-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 387.8°Cat760mmHg
• Flash Point: 202.5°C
• Appearance: /
• Density: 1.487g/cm³
• Vapor Pressure: 4.3E-07mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: cyclopent-3-ene-1,1-dicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: cyclopent-3-ene-1,1-dicarboxylic acid(88326-51-6)
• EPA Substance Registry System: cyclopent-3-ene-1,1-dicarboxylic acid(88326-51-6)

Safety Data

• Hazardous Substances Data: 88326-51-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H8O4/c8-5(9)7(6(10)11)3-1-2-4-7/h1-2H,3-4H2,(H,8,9)(H,10,11)

Upstream product

• 7686-78-4 diethyl 2-vinylcyclopropane-1,1-dicarboxylate 
• 4372-31-0 2,2-diallylmalonic acid 
• 1476-11-5 Z-1,4-dichlorobutene 
• 108-59-8 malonic acid dimethyl ester 
• 84646-68-4 Dimethyl 3-cyclopentene-1,1-dicarboxylate 
• 21622-00-4 Cyclopent-3-ene-1,1-dicarboxylic acid diethyl ester 
• 105-53-3 diethyl malonate 

Downstream Products

• 58101-60-3 methyl cyclopent-3-ene-1-carboxylate 
• 1004764-73-1 benzyl (2-{4-[3-(2-methylpyrrolidin-1-yl)propoxy]phenyl}-5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-5-yl)carbamate 
• 1004764-72-0 benzyl {2-[4-(3-chloropropoxy)phenyl]-5,6-dihydro-4H-cyclopenta[d][1,3]thiazol-5-yl}carbamate 
• 89415-65-6 trans-3,4-dibromocyclopentane-1-carboxylic acid 
• 7686-79-5 3-cyclopentenecarboxylic acid phenyl amide 
• 99-14-9 tricarallylic acid 
• 76909-91-6 rel-(1R,5R)-5-(hydroxymethyl)cyclopent-2-en-1-ol 
• 88710-88-7 (3-cyclopentenylmethyl)methylphenylsilane 
• 25125-21-7 4-(hydroxymethyl)cyclopentene 
• 922166-21-0 1-bromo-2-(cyclopent-3-enylmethyl)-3,4-difluorobenzene 
• 7686-77-3 3-cyclopentene-1-carboxylic acid 

Relevant articles and documents

Acetamide scanning around bicyclic thiazoles: SAR at the H3 receptor

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Design and synthesis of spiro-heterocycles by ring-closing metathesis

Synthesis of diverse spiro-heterocyclic compounds via the ring-closing (RCM) metathesis approach is described. Specifically, synthesis of various derivatives of barbituric acid, Meldrum's acid, tetronic acid and thiotetronic acid are described by RCM approach.

Occlusion of Grubbs' catalysts in active membranes of polydimethylsiloxane: Catalysis in water and new functional group selectivities

The Grubbs' first and second generation catalysts were occluded into cross-linked slabs of polydimethylsiloxane with volumes from 1 mm3 to 1 cm3 by swelling the polymer with catalyst and methylene chloride. Methylene chloride was evaporated under vacuum to yield occluded catalysts where their solvent was polydimethylsiloxane. These occluded catalysts were reacted with alkenes dissolved in H2O or H2O/MeOH mixtures that diffused into the polydimethylsiloxane to react by ring-closing metathesis and cross metathesis. Control experiments revealed that the catalysts remained occluded and metathesis did not occur in the solvent. Occlusion of these catalysts allowed commercially available Grubbs' catalysts to be used with H2O as the solvent while isolating the H2O sensitive ruthenium methylidene from exposure to H2O. Functional group selective experiments were carried out where the polydimethylsiloxane was an "active" membrane to exclude salts. Polydimethylsiloxane is a hydrophobic polymer, so the deprotonated salt of diallylmalonic acid did not diffuse into it while a diallylether diffused into it and reacted by metathesis. Thus, by controlling the polarity of reagents their reactivity can be controlled owing to the properties of polydimethylsiloxane rather than those of the Grubbs' catalysts. Occlusion of catalysts in polydimethylsiloxane has been shown to add new selectivities to mature catalysts. Copyright