88335-87-9Relevant articles and documents
Asymmetric synthesis of novel β-substituted β-methoxyacrylates bearing a chiral 1,2-cis-disubstituted cyclopropane substructure
Hasegawa, Daiju,Uchiro, Hiromi,Kobayashi, Susumu
, p. 7185 - 7187 (2002)
The first asymmetric synthesis of β-substituted β-methoxyacrylate bearing a chiral 1,2-cis-disubstituted cyclopropane ring as a 'conformationally locked' substructure, by Claisen condensation and E-selective Wittig reaction was successfully achieved.
BICYCLIC COMPOUNDS AS INHIBITORS OF PD1/PD-L1 INTERACTION/ACTIVATION
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Paragraph 00098, (2019/10/04)
The compounds of Formula I is described herein along with their polymorphs, stereoisomers, tautomers, prodrugs, solvates, and pharmaceutically acceptable salts thereof. The compounds described herein, their polymorphs, stereoisomers, tautomers, prodrugs, solvates, and pharmaceutically acceptable salts thereof are bicyclic compounds that are inhibitors of PD-1/PD-L1 interaction/activation.
CYCLOPROPANECARBOXYLIC ACID GPR120 MODULATORS
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Page/Page column 0309; 0310, (2017/09/21)
The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein coupled receptor modulators which may be used as medicaments
AROMATIC RING COMPOUND
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Paragraph 0304, (2015/03/28)
The present invention provides an aromatic ring compound having a melanin-concentrating hormone receptor antagonistic action and useful as an agent for the prophylaxis or treatment of obesity and the like. The present invention relates to a compound represented by the formula wherein each symbol as defined in the specification, or a salt thereof.
