88382-49-4

Usage

InChI:InChI=1/C14H12O2S/c15-14(16)12-8-6-11(7-9-12)10-17-13-4-2-1-3-5-13/h1-9H,10H2,(H,15,16)

Upstream product

• 1642-81-5 p-(chloromethyl)benzoic acid 
• 930-69-8 sodium thiophenolate 
• 6232-88-8 4-bromomethylbenzoic Acid 
• 108-98-5 thiophenol 
• 31719-79-6 4-(iodomethyl)benzoic acid 

Downstream Products

• 71964-92-6 4-<(Phenylsulfonyl)methyl>benzoic acid 
• 110046-28-1 4-<(Phenylsulfinyl)methyl>benzoic acid 
• 1257086-84-2 4-[(phenylthio)methyl]benzoyl chloride 
• 88393-10-6 methyl 4-amino-4-deoxy-10-(phenylsulfonyl)-8,10-dideazapteroate 
• 88393-08-2 α-methyl-p-carbomethoxybenzyl phenyl sulfoxide 
• 84851-57-0 methyl α-methyl-p-<(phenylthio)methyl>benzoate 
• 59584-27-9 Methyl 4-<(phenylsulfonyl)methyl>benzoate 
• 1076-96-6 methyl 4-vinylbenzoate 
• 88393-07-1 methyl 4-<(phenylthio)methyl> benzoate 

Relevant academic research and scientific papers

ARYLSULFANYL COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS

Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are also provided.

Substituted N-aryl heterocycles, process for their preparation and their use as medicaments

The invention relates to substituted N-aryl heterocycles and to the physiologically tolerated salts and physiologically functional derivatives thereof. Compounds of the formula I in which the radicals have the stated meanings, the N-oxides and the physiologically tolerated salts thereof and process for the preparation thereof are described. The compounds are suitable for example as anorectic agents.

Kinetics of the reaction of sodium arylthiolates with nitro-carboxybenzyl halide derivatives

The rate constants for the reactions of 4-halomethyl-3-nitrobenzoic acids, the nonnitro derivatives, and their ethyl esters with arylthiolates were measured at different temperatures. It was found that the retardation in rate constants compared to benzyl halides is due to the electrostatic repulsion between the electronegative substituents (COO- and/or NO2) in the substrates and thiolate ions Good correlations between log K2 values of the acids and carbon basicities of thiolates were found while log k2 values of the esters show good straight lines with Hammett a constants, pKa. and carbon basicities of arylthiolates.

Synthesis and Spectral Studies of Some New Sulfides, Sulfoxides, and Sulfones. 2

New substituted benzylphenyl sulfides, sulfoxides, and sulfones have been synthesized.Their structures were confirmed by IR, (1)H NMR, and mass spectra.

Synthesis and antifolate properties of 10-alkyl-8,10-dideazaminopterins

The synthesis of 10-alkyl analogues of the potent antitumor agent 8,10-dideazaminopterin is described. Alkylation of appropriate α-alkyl homoterephthalate esters with 2,4-diamino-6-(bromomethyl)-8-deazapteridine afforded 10-alkyl-10-carboxy-4-amino-4-deox