884-29-7

Upstream product

• 861779-49-9 N-(α-bromo-benzyl)-2-chloro-aniline 
• 100-52-7 benzaldehyde 
• 95-51-2 o-chloroaniline 
• 774-48-1 (diethoxymethyl)benzene 
• 100-51-6 benzyl alcohol 
• 88-73-3 2-Chloronitrobenzene 
• 108-88-3 toluene 
• 100-46-9 benzylamine 
• 95-55-6 2-amino-phenol 
• 13381-65-2 α-Bromobenzyl benzoate 
• 201024-81-9 C,N-diphenylnitrone 
• 110788-33-5 triphenylarsenazo-o-chlorophenyl 
• 64846-63-5 1-(o-chlorophenyl)-4-phenyl-1,2-diazabutadiene 

Downstream Products

• 98018-66-7 N-benzyl-2-chloroaniline 
• 115228-56-3 N,N'-bis-(2-chloro-phenyl)-bibenzyl-α,α'-diyldiamine 
• 1241382-69-3 2-phenylmethylideneamino-3',4',5'-trifluorobiphenyl 
• 915416-45-4 3’,4’,5’-trifluoro-[1,1’-biphenyl]-2-amine 
• 120758-01-2 C₁₅H₁₆ClN 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

Photocatalytic one-pot multidirectional N-alkylation over Pt/D-TiO2/Ti3C2: Ti3C2-based short-range directional charge transmission

Visible-light-induced one-pot, multistep, and chemoselectivity adjustable reactions highlight the economical, sustainable, and green process. Herein, we report Pt nanoparticles dispersed on S and N co-doped titanium dioxide/titanium carbide (MXene) (3%Pt/

Highly efficient and selective one-pot tandem imine synthesis via amine-alcohol cross-coupling reaction catalysed by chromium-based MIL-101 supported Au nanoparticles

One-pot tandem synthesis of imines from alcohols and amines is regarded as an effective, economic and green approach under mild conditions. In this work, Au nanoparticles (NPs) dispersed on MIL-101 (Au/MIL-101) were demonstrated as highly active and selective bifunctional heterogeneous catalyst for production of various imine derivatives with excellent yields, via amine-alcohol cross-coupling reaction at 343 K in an open flask under an Ar atmosphere. Various physicochemical techniques, including inductively coupled plasma optical emission spectroscopy (ICP-OES), powder X-ray diffraction (P-XRD), X-ray photoelectron spectroscopy (XPS) transmission electron microscopy (TEM) and N2 adsorption-desorption, were used to characterize of the Au/MIL-101 catalyst. The obtained bifunctional catalyst is highly active and selective towards one-pot imine formation and exhibited the highest TOF (30.15-51.47 h?1) among all the ever-reported MOF-supported Au catalysts. The reaction mechanism of the imine formation from alcohol and amine over Au/MIL-101 catalyst was proposed. Mechanism experiment results demonstrate that Au NPs highly effective in activating oxidation of benzyl alcohol to benzaldehyde while the Lewis acid sites on MIL-101 catalyzed the second condensation step without interfering with the oxidation step. As a result, the excellent catalytic performance of Au/MIL-101 can be ascribed to the synergistic effect between Au NPs with Lewis acid sites in MIL-101.

Catalyst- And solvent-free efficient access to: N -alkylated amines via reductive amination using HBpin

A sustainable approach which works under catalyst- and solvent-free conditions for the synthesis of structurally diverse secondary amines has been uncovered. This one-pot protocol works efficiently at room temperature and is compatible with a wide range of sterically and electronically diverse aldehydes and primary amines. Notably, this simple process offers scalability, excellent functional group tolerance, chemoselectivity, and is also effective at the synthesis of biologically relevant molecules. This journal is

Method for synthesizing aluminum phosphate molecular sieve catalytic imine

The invention discloses a method for catalyzing synthesis of an imine by using an aluminum phosphate molecular sieve, and belongs to the technical field of catalytic synthesis of imines. Under the action of an HP-MeAlPO-5 molecular sieve, air or oxygen is used as an oxidant, and an amine and an alcohol which contain different substituents are directly subjected to oxidative coupling to synthesizethe imine under mild conditions. According to the method provided by the invention, the reaction conditions of the adopted catalytic system are mild, and the TOF is high; a reaction can efficiently catalyze the synthesis of the imine at room temperature under air; and the method can adopt transition metals, which are cheap and easy to obtain, such as iron, cobalt and nickel as a molecular sieve dopant, and the availability of the molecular sieve is improved.

Method of synthesizing imine and amine compounds by means of borrowing-hydrogen reduction coupling

The invention belongs to energy and chemical industry and particularly relates to a method of synthesizing imine and amine compounds by means of borrowing-hydrogen reduction coupling by using a nitrogen-doped hierarchical-porous biomass-based carbon material supported catalyst. The method includes the steps of: under a seal reaction condition, adding a nitro-aromatic hydrocarbon compound, benzyl alcohol compounds with different substituent groups, the supported catalyst, methylbenzene and potassium tert-butoxide; performing a reaction at 50-150 DEG C for 4-24 h, cooling the product to room temperature and filtering a reaction liquid to obtain the imine compound represented in the formula (1) or the amine compound represented in the formula (2). The raw materials of the catalyst are regenerable resources, are widely distributed, are green and environment-friendly, are easy to prepare and abundant in sources, and are low in cost; the catalyst can be recycled without deactivation and is stable to air, water and heat. By means of the supported metal catalyst, the conversion rate of the borrowing-hydrogen reduction coupling reaction on the nitro-compound and alcohol to prepare the iminecompounds is higher than 99%, and yield can reach 90-60%; the conversion rate of same to prepare the amine compounds is higher than 99%, and yield can reach 90-60%.

Preparation method of fluorine-containing benzidine

The invention relates to the field of organic synthesis, in particular to a preparation method of fluorine-containing benzidine. The invention provides the preparation method of the fluorine-containing benzidine. The preparation method comprises the follo

Preparation method for imine compounds

The invention relates to a preparation method for imine compounds. The preparation method comprises the following concrete steps: with toluene or derivatives thereof and aminated compounds as reaction substrates, adding an oxygen source under the action of a catalyst; putting the above-mentioned substances into a pressure container, enclosing the pressure container and carrying out a stirring reaction at 50 to 150 DEG C for 6 to 24 h; and carrying out oxidative condensation so as to prepare the imine compounds. The method is characterized in that a metal oxide is used as the catalyst. According to the method, raw materials are cheap and easily available; the prepared imine compounds are easily separable from the catalyst; the catalyst can be cyclically used; reaction process is simple, controllable and easy to operate; and the yield of the imine compounds is as high as 90%.

Activated Carbon Supported Ruthenium Nanoparticles Catalyzed Synthesis of Imines from Aerobic Oxidation of Alcohols with Amines

Abstract: Imines were synthesized from the cross-coupling of alcohols with amines catalyzed by activated carbon (AC) supported ruthenium nanoparticles under atmospheric molecular oxygen without aid of any additives. The readily prepared catalyst 5%Ru/AC showed good to excellent (yield > 90%) performances in the reaction of aromatic and heterocyclic alcohols with various amines, such as aromatic, aliphatic and heterocyclic amines. This protocol is simple, efficient, and environmentally friendly, and the catalyst can be easily recovered without major ruthenium loss. Graphical Abstract: Imines were synthesized from the cross-coupling of alcohols with amines catalyzed by activated carbon (AC) supported ruthenium nanoparticles under atmospheric molecular oxygen without aid of any additives. This protocol is simple, efficient, and environment friendly, and the readily prepared catalyst 5%Ru/AC showed good to excellent performances in the reaction of aromatic and heterocyclic alcohols with various amines, such as aromatic, and aliphatic amines. [Figure not available: see fulltext.]

Aerobic oxidation of amines to imines catalyzed by a ruthenium complex under solvent-free conditions

A ruthenium complex [Et3NH]2[Ru(dipic)Cl3] showed high efficiency in the homo-coupling of primary amines and cross-coupling of benzylamine with anilines and aliphatic amines to the corresponding imines under air and solvent-free conditions. This protocol is an atom-economical green process and tolerates various substrates bearing both electron-donating and electron-withdrawing substituents.

Load manganese oxidizing catalytic chipboard spreading method for one-step synthesis of imines

The invention belongs to the technical fields of chemistry and chemical engineering, and concretely relates to a method for one step synthesis of imine through catalyzing alcohol and amine by supported manganese oxide. A reaction of alcohol and amine is carried out in a solvent or solvent-free state at 60-90DEG C for 6-48h with the supported manganese oxide as a catalyst and molecular oxygen or air as an antioxidant to realize one step synthesis of a corresponding imine compound. The valence of manganese in the catalyst is +2, +3 or +4, the general formula of the catalyst is MnOx, and a carrier is hydroxyapatite (Ca10(PO4)6(OH)2). The catalyst still has very good activity and selectivity after the catalyst is reused at least 9 times. The catalyst used in the method has the characteristics of simple preparation, cheapness, high reaction selectivity and environmental protection.