88407-66-3

Upstream product

• 14224-99-8 2-methyl-4,5-diphenyloxazole 
• 2735-14-0 1,2-bis(4-nitrophenyl)acetylene 
• 75-05-8 acetonitrile 

Downstream Products

• 92968-29-1 4,4'-(2-methyl-oxazole-4,5-diyl)-bis-aniline 
• 92872-15-6 4-[2-methyl-4-(4-nitro-phenyl)-oxazol-5-yl]-aniline 
• 6067-45-4 4,4'-dinitrobenzil 
• 92795-10-3 4,5-bis-(4-iodo-phenyl)-2-methyl-oxazole 
• 93989-33-4 4-(4-bromophenyl)-5-(4-chlorophenyl)-2-methyloxazole 
• 92796-21-9 5-(4-bromo-phenyl)-4-(4-chloro-phenyl)-2-methyl-oxazole 
• 58764-21-9 4,4'-(2-methyl-oxazole-4,5-diyl)-bis-benzoic acid dimethyl ester 
• 95813-55-1 4-[2-methyl-4-(4-nitro-phenyl)-oxazol-5-yl]-benzoic acid methyl ester 
• 93327-05-0 4-[2-methyl-4-(4-nitro-phenyl)-oxazol-5-yl]-benzoic acid 
• 88590-47-0 4,4'-(2-methyl-oxazole-4,5-diyl)-bis-benzoic acid 
• 94960-14-2 4,4'-(2-methyl-oxazole-4,5-diyl)-bis-benzamide 
• 93329-16-9 4-[2-methyl-4-(4-nitro-phenyl)-oxazol-5-yl]-benzonitrile 
• 93819-35-3 4,4'-(2-methyloxazole-4,5-diyl)dibenzonitrile 
• 92872-85-0 4-[5-(4-bromo-phenyl)-2-methyl-oxazol-4-yl]-aniline 

Relevant academic research and scientific papers

Iodonium Cation-Pool Electrolysis for the Three-Component Synthesis of 1,3-Oxazoles

The synthesis of 1,3-oxazoles from symmetrical and unsymmetrical alkynes was realized by an iodonium cation-pool electrolysis of I2 in acetonitrile with a well-defined water content. Mechanistic investigations suggest that the alkyne reacts with the acetonitrile-stabilized I+ ions, followed by a Ritter-type reaction of the solvent to a nitrilium ion, which is then attacked by water. The ring closure to the 1,3-oxazoles released molecular iodine, which was visible by the naked eye. Also, some unsymmetrical internal alkynes were tested and a regioselective formation of a single isomer was determined by two-dimensional NMR experiments.

HEPATITIS C VIRUS INHIBITORS

The present disclosure is generally directed to antiviral compounds, and more specifically directed to compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such compounds, and methods for inhibiting the function of the NS5A protein

STRUCTURES IN SOLUTION OF ADDUCTS OF HEXAMETHYLPHOSPHORUS TRIAMIDE AND SUBSTITUTED BENZILS

Hexamethylphosphorus triamide has been allowed to react with p,p'-dinitrobenzil, p-chlorobenzyl, p,p'-difluorobenzil, p,p'-dimethylbenzil and p,p'-dimethoxybenzil.All of these materilas in benzene-d6 had negative δ 31P chemical shifts except for the p,p'-