88484-88-2

Upstream product

• 19842-57-0 2,5-dimethyl-3-phenylfurane 
• 75-36-5 acetyl chloride 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 123-54-6 acetylacetone 
• 70244-87-0 3-(1-phenylprop-2-yn-1-yl)pentane-2,4-dione 
• 90-63-1 (RS)-1-hydroxy-1-phenylpropan-2-one 
• 98-80-6 phenylboronic acid 
• 1134781-54-6 3-acetyl-4-phenyl-hexane-2,5-dione 
• 705-60-2 (2-nitroprop-1-enyl)benzene 
• 89530-34-7 1-phenyl-3-trimethylsilylprop-2-yn-1-ol 
• 16169-88-3 1-phenylprop-2-ynyl acetate 
• 58321-79-2 (Z)-(2-nitroprop-2-en-1-yl)benzene 

Downstream Products

• 104406-10-2 2,5-dimethyl-4-phenyl-3-<1-oxo-3-(4-amino-3-nitrophenyl)-2-propenyl>furan 
• 104406-31-7 3-(3,4-Diamino-phenyl)-1-(2,5-dimethyl-4-phenyl-furan-3-yl)-propan-1-one 
• 104406-14-6 Methyl 5(6)-<3-(2,5-dimethyl-4-phenylfur-3-yl)-3-oxopropyl>benzimidazole-2-carbamate 

Relevant academic research and scientific papers

Copper-Catalyzed Three-Component Reactions of α-Ketoaldehyde, 1,3-Dicarbonyl Compound, and Organic Boronic Acid in Water: A Route to 1,4-Diketones

A novel three-component reaction of α-ketoaldehydes, 1,3-dicarbonyl compounds, and organic boronic acids catalyzed by CuO in water has been developed to give a wide range of products containing 1,3/1,4-diketones. The method has some advantages such as the

Diversified Synthesis of Furans by Coupling between Enols/1,3-Dicarbonyl Compounds and Nitroolefins: Direct Access to Dioxa[5]helicenes

A versatile method for the diversified synthesis of furans and arenofurans has been developed that proceeds through K2CO3-promoted cyclization between enols/1,3-dicarbonyl compounds and nitroolefins at reflux in EtOH. This facile method has been successfully employed in the synthesis of benzotrifuran derivatives, which are useful hole-transporting materials. This procedure also provides direct access to dioxa[5]helicenes. This reaction offers a broad substrate scope, uses an inexpensive base and environmentally benign solvent, and is operationally simple.

Synthesis of tetrasubstituted NH pyrroles and polysubstituted furans via an addition and cyclization strategy

The FeCl3-catalyzed addition and cyclization of enamino esters with nitroolefins provides a straightforward and general method for the synthesis of tetrasubstituted NH pyrroles. This novel method tolerates a wide range of functionality, and allows for rapid elaboration of the nitroolefins into a variety of substituted pyrroles in good yields. Further, an efficient KOAc-promoted addition and cyclization protocol toward substituted furans has been described as well. Georg Thieme Verlag Stuttgart · New York.

Condensation of propargylic alcohols with 1,3-dicarbonyl compounds and 4-hydroxycoumarins in ionic liquids (ILs)

Propargylic alcohols are activated toward 1,3-diketones by Lewis or Br?nsted acidic ionic liquids (ILs) without an added catalyst, but significantly better conversions are achieved with metallic triflates [in particular Sc(OTf)3 and Ln(OTf)sub

Direct synthesis of highly substituted furans from acyloins and active methylene compounds catalyzed by bismuth triflate

Bi(OTf)3 was found to be an effective catalyst for a tandem condensation/cyclization of acyloins and β-diketones or β-keto esters to afford highly substituted furans in good yields.

Sequential gold-catalyzed reactions of 1-phenylprop-2-yn-1-ol with 1,3-dicarbonyl compounds

A variety of sequential gold-catalyzed reactions of 1-phenylprop-2-yn-1-ol with 1,3-dicarbonyl compounds are directed towards different outcomes by a suitable choice of the catalytic system, feature of 1,3-dicarbonyl and reaction conditions.

Synthesis of tetrasubstituted furans via In-catalyzed propargylation of 1,3-dicarbonyl compounds-cyclization tandem process

An efficient method to synthesize tetrasubstituted furans using simple starting materials such as propargylic alcohols and 1,3-dicarbonyl compounds has been developed. It was discovered that InCl3 could catalyze this transformation efficiently

FeCl3-catalyzed propargylation-cycloisomerization tandem reaction: A facile one-pot synthesis of substituted furans

An efficient FeCl3-catalyzed tandem propargylation- cycloisomerization reaction of propargylic alcohols or acetates with 1,3-dicarbonyl compounds, leading to the synthesis of substituted furans, has been developed. Georg Thieme Verlag Stuttgart

A novel propargylation/cycloisomerization tandem process catalyzed by a ruthenium(II)/trifluoroacetic acid system: One-pot entry to fully substituted furans from readily available secondary propargylic alcohols and 1,3-dicarbonyl compounds

A simple and highly efficient method for the preparation of tetrasubstituted furans starting from readily accessible propargylic alcohols and commercially available 1,3-dicarbonyl compounds has been developed. The process, which proceeds in a one-pot mann

STUDIES ON ORGANOPHOSPHORUS COMPOUNDS. 67. REACTIONS OF α-NITROALKENES WITH COMPOUNDS BEARING ACTIVE METHYLENE GROUPS. A NOVEL AND CONVENIENT SYNTHESIS OF 2-ISOXAZOLINE DERIVATIVES

Reaction of α-nitroalkenes and compounds bearing an active methylene group followed by subsequent addition of trimethylchlorosilane leads to a series of 2-isoxazoline derivatives in good yield.The reaction proceeded through the formations of an alkene and