885123-33-1 Usage
Description
(R)-3-(4-fluorophenyl)-3-hydroxypropionic acid methyl ester is a chiral methyl ester derivative of 3-(4-fluorophenyl)-3-hydroxypropionic acid, belonging to the class of organic compounds known as hydroxy fatty acids. The (R)-enantiomer is the active form, and it is widely utilized in the synthesis of pharmaceutical compounds, serving as an intermediate in the production of various drugs. Its structural properties and potential biological activities also make it a promising candidate for applications in medicine, biochemistry, and pharmacology.
Uses
Used in Pharmaceutical Synthesis:
(R)-3-(4-fluorophenyl)-3-hydroxypropionic acid methyl ester is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique structural properties and chirality enable the creation of specific drug molecules with targeted therapeutic effects.
Used in Medicine:
In the medical field, (R)-3-(4-fluorophenyl)-3-hydroxypropionic acid methyl ester is used as a compound with potential biological activities. Its chiral nature allows for the development of drugs that can interact with specific biological targets, potentially leading to more effective treatments for various diseases and conditions.
Used in Biochemistry:
(R)-3-(4-fluorophenyl)-3-hydroxypropionic acid methyl ester is employed as a research tool in biochemistry to study the interactions between molecules and biological systems. Its structural properties can provide insights into the mechanisms of various biological processes and contribute to the understanding of complex biochemical pathways.
Used in Pharmacology:
In pharmacology, (R)-3-(4-fluorophenyl)-3-hydroxypropionic acid methyl ester is used as a compound with potential applications in drug development. Its chirality and structural properties make it a valuable asset in the design and synthesis of new drugs with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 885123-33-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,1,2 and 3 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 885123-33:
(8*8)+(7*8)+(6*5)+(5*1)+(4*2)+(3*3)+(2*3)+(1*3)=181
181 % 10 = 1
So 885123-33-1 is a valid CAS Registry Number.
885123-33-1Relevant articles and documents
Thermomorphic system with non-fluorous phase-tagged Ru(BINAP) catalyst: Facile liquid/solid catalyst separation and application in asymmetric hydrogenation
Huang, Yi-Yong,He, Yan-Mei,Zhou, Hai-Feng,Wu, Lei,Li, Bao-Lin,Fan, Qing-Hua
, p. 2874 - 2877 (2006)
The thermomorphic BINAP derivative 1 tagged with long alkyl chains was prepared from (S)-5,5′-diamino BINAP and applied to Ru-catalyzed asymmetric hydrogenation of β-ketoesters under homogeneous conditions in 3:1 (v/v) ethanol/ 1,4-dioxane at 60 °C with high enantioselectivity (up to 98% ee). Results indicated that the Ru(1) catalyst was easily recovered by simple cooling and precipitation and could be used for at least four cycles without any loss of enantioselectivity.
Iridium-catalyzed asymmetric hydrogenation of β-keto esters with new phenethylamine-derived tridentate P,N,N-ligands
Wei, De-Quan,Chen, Xiu-Shuai,Hou, Chuan-Jin,Hu, Xiang-Ping
supporting information, p. 237 - 243 (2019/01/21)
A new class of phenethylamine-derived tridentate P,N,N-ligands has been successfully developed. These ligands exhibited good performance in the Ir-catalyzed asymmetric hydrogenation of β-keto esters, affording the corresponding β-hydroxy esters in moderat
Iridium-catalyzed asymmetric hydrogenation of β-keto esters with f-amphox ligands
Qin, Chao,Chen, Xiu-Shuai,Hou, Chuan-Jin,Liu, Hongzhu,Liu, Yan-Jun,Huang, De-Zhi,Hu, Xiang-Ping
supporting information, p. 672 - 676 (2018/02/19)
The iridium-catalyzed asymmetric hydrogenation of β-keto esters with chiral tridentate P,N,N-ligands (f-amphox) has been developed. Under the optimized conditions, a wide range of β-keto esters can be hydrogenated smoothly, affording the corresponding β-hydroxy esters in good to excellent enantioselectivities (up to 95% ee).
