88773-69-7

Basic information

• Product Name: Ethanone, 2,2-dichloro-1-(1-methyl-1H-pyrrol-2-yl)- (9CI)
• Synonyms: Ethanone, 2,2-dichloro-1-(1-methyl-1H-pyrrol-2-yl)- (9CI)
• CAS NO: 88773-69-7
• Molecular Formula: C₇H₇Cl₂NO
• Molecular Weight: 192.04258
• Product Categories: ACETYLHALIDE
• Mol File: 88773-69-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 65-66 °C
• Boiling Point: 271.9±25.0 °C(Predicted)
• Appearance: /
• Density: 1.34±0.1 g/cm3(Predicted)
• PKA: -8.87±0.70(Predicted)
• CAS DataBase Reference: Ethanone, 2,2-dichloro-1-(1-methyl-1H-pyrrol-2-yl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2,2-dichloro-1-(1-methyl-1H-pyrrol-2-yl)- (9CI)(88773-69-7)
• EPA Substance Registry System: Ethanone, 2,2-dichloro-1-(1-methyl-1H-pyrrol-2-yl)- (9CI)(88773-69-7)

Safety Data

• Hazardous Substances Data: 88773-69-7(Hazardous Substances Data)

Upstream product

• 21898-65-7 1-methyl-2-trichloroacetyl-1H-pyrrole 
• 100-59-4 phenylmagnesium chloride 
• 6749-78-6 4-methylphenylmagnesium iodide 
• 112219-63-3 (4-methoxyphenyl)magnesium iodide 
• 16002-63-4 phenylmagnesium iodide 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 1426338-83-1 2,2-dichloro-3-hydroxy-1-(1-methyl-1H-pyrrol-2-yl)-3-phenylpropan-1-one 
• 1426338-84-2 2,2-dichloro-3-hydroxy-3-(4-methoxyphenyl)-1-(1-methyl-1H-pyrrol-2-yl)propan-1-one 
• 1426338-92-2 2,2-dichloro-1-(1-methyl-1H-pyrrol-2-yl)-3-phenylpropane-1,3-dione 
• 1426338-90-0 2,2-dichloro-1-(1-methyl-1H-pyrrol-2-yl)-3-(4-nitrophenyl)propane-1,3-dione 
• 1426338-89-7 2,2-dichloro-1-(1-methyl-1H-pyrrol-2-yl)-3-(4-nitrophenyl)propan-1-one 
• 1426338-88-6 2,2-dichloro-3-hydroxy-1-(1-methyl-1H-pyrrol-2-yl)-3-(4-nitrophenyl)propan-1-one 
• 1426338-87-5 2,2-dichloro-3-hydroxy-1-(1-methyl-1H-pyrrol-2-yl)-3-(perfluorophenyl)propan-1-one 
• 1426338-85-3 2,2-dichloro-3-hydroxy-3-(4-iodophenyl)-1-(1-methyl-1H-pyrrol-2-yl)propan-1-one 

Relevant articles and documents

Reduction of 2,2,2-trichloro-1-arylethanones by RMgX: Mechanistic investigation and the synthesis of substituted α,α-dichloroketones

2,2,2-Trichloro-1-arylethanones undergo high yielding reductions to the corresponding 2,2-dichloro-1-arylethanones in the presence of RMgX. A single electron transfer mechanism for the reaction is proposed based on trapping experiments. Reaction of the intermediate enolates with a range of electrophiles is described, providing a convenient route to substituted α,α- dichloro-β-hydroxyketones and related molecules. The Royal Society of Chemistry 2013.