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Usage

Uses

Used in Pharmaceutical Industry:
3-(4-Hydroxyphenyl)-2-phenylpropionic acid is used as an anti-inflammatory agent for the treatment of conditions characterized by pain and inflammation, such as arthritis and menstrual cramps. It is valued for its ability to reduce the production of pro-inflammatory chemicals, thereby providing relief to patients suffering from these conditions.
Used in Pain Management:
In the context of pain management, 3-(4-Hydroxyphenyl)-2-phenylpropionic acid serves as an analgesic, helping to alleviate discomfort arising from various sources. Its effectiveness in reducing pain makes it a common choice for healthcare professionals when addressing chronic pain issues.

InChI:InChI=1/C15H14O3/c16-13-8-6-11(7-9-13)10-14(15(17)18)12-4-2-1-3-5-12/h1-9,14,16H,10H2,(H,17,18)/t14-/m0/s1

Upstream product

• 4314-68-5 3-(4-methoxyphenyl)-2-phenylpropionic acid 
• 6962-09-0 (E)-3-(4-hydroxyphenyl)-2-phenylacrylic acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 
• 103-82-2 phenylacetic acid 
• 623-11-0 1-methyl-4-nitrosobenzene 
• 577-91-3 3-(4-hydroxy-3,5-diiodo-phenyl)-2-phenyl-propionic acid 
• 879008-22-7 3c-(4-hydroxy-phenyl)-2-phenyl-acrylic acid 
• 6968-77-0 3-(4-methoxyphenyl)-2-phenylacrylic acid 

Downstream Products

• 57151-46-9 1-phenyl-2-[4-(phenylmethoxy)phenyl]-ethylamine 
• 854673-51-1 3-(4-benzyloxy-phenyl)-2-phenyl-propionic acid amide 
• 501031-62-5 3-(4-hydroxy-phenyl)-2-phenylpropionic acid methyl ester 
• 125036-76-2 3-(4-benzyloxy-phenyl)-2-phenyl-propionic acid 
• 577-91-3 3-(4-hydroxy-3,5-diiodo-phenyl)-2-phenyl-propionic acid 

Relevant academic research and scientific papers

Heterogeneous enantioselective hydrogenation of hydroxy-substituted (E)-2,3-diphenylpropenoic acids over Pd/Al2O3 modified by cinchonidine

The enantioselective hydrogenation of (E)-2,3-diphenylpropenoic acids substituted by hydroxyl group has been studied over Pd/Al2O 3 catalyst modified by cinchonidine. The effect of the acidic hydroxyl substituents was compared with that of the methoxy group in the same position. The para-hydroxyl substituent on the 3-phenyl ring had similar effect on the enantioselectivity as the methoxy group, whereas the meta positioned decreased the optical purity of the saturated acid. This was explained by different origin of the increase in the enantioselectivity obtained in the presence of electron releasing substituents in these positions. Although, the para-hydroxyl group on the 2-phenyl ring had beneficial influence on the enantioselectivity of the hydrogenation of the mono-substituted acid, in the presence of fluorine or hydroxyl group on the 3-phenyl ring the effect of the two substituents was not additive. This study demonstrated that the cinchonidine-modified Pd catalyst is appropriate for the preparation of several hydroxy-substituted 2,3-diphenylpropionic acids in good optical purities, extending the scope of this catalytic system to new types of versatile chiral building blocks.