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1H-Pyrazolo[3,4-b]quinoline, 3-methyl-1-phenyl- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

894-88-2

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894-88-2 Usage

Compound type

Organic chemical compound

Family

Pyrazoloquinolines (heterocyclic compounds with a pyrazole ring fused to a quinoline ring system)

Structural features

Methyl group at the 3-position of the pyrazoloquinoline core, phenyl group at the 1-position

Potential applications

Pharmaceutical and medicinal chemistry (due to unique structure and potential biological activities)

Importance

May serve as a drug candidate or valuable building block in organic synthesis (pending further research and exploration of properties)

Check Digit Verification of cas no

The CAS Registry Mumber 894-88-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,9 and 4 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 894-88:
(5*8)+(4*9)+(3*4)+(2*8)+(1*8)=112
112 % 10 = 2
So 894-88-2 is a valid CAS Registry Number.

894-88-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-methyl-1-phenylpyrazolo[3,4-b]quinoline

1.2 Other means of identification

Product number -
Other names 1-phenyl-3-methyl-pyrazolo<3,4-b>quinoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:894-88-2 SDS

894-88-2Downstream Products

894-88-2Relevant academic research and scientific papers

DMSO as a Methine Source in TFA-Mediated One-Pot Tandem Regioselective Synthesis of 3-Substituted-1-Aryl-1 H-Pyrazolo-[3,4- b]quinolines from Anilines and Pyrazolones

Yadav, Pushpendra,Awasthi, Annapurna,Gokulnath, Sabapathi,Tiwari, Dharmendra Kumar

, p. 2658 - 2666 (2021/02/01)

An acid-mediated and DMSO participant one-pot tandem synthesis of 3-substituted-1-aryl-1H-pyrazolo-[3,4- b]quinoline from readily available anilines and pyrazolones was achieved. This method enables regioselective construction of the valuable heterocycles under transition-metal and oxidant-free conditions in which DMSO acts as a methine source as well as solvent making this process an environmentally benign approach. A broad range of diversely substituted aryl amines and pyrazolines are successfully employed in this reaction to access a series of pyrazolo[4,3-c]quinolones through a novel cascade mechanism. Furthermore, the application and mechanistic studies of the present methodology also demonstrated.

Facile and Regioselective Synthesis of Substituted 1H-Pyrazolo[3,4-b]quinolines from 2-Fluorobenzaldehydes and 1H-Pyrazol-5-amines

Szlachcic, Pawe?,Kucharek, Mateusz,Jarosz, Bo?ena,Danel, Andrzej,Stadnicka, Katarzyna

, p. 1729 - 1745 (2017/05/29)

The present article concerns the scope and limitations of the regioselective condensation of 2-fluorobenzaldehydes with 1H-pyrazol-5-amines, leading to the synthesis of substituted 1H-pyrazolo[3,4-b]quinolines (PQ), in the presence of a base catalyst (DAB

Synthesis, electrochemical, photophysical, and electroluminescent properties of organic dyes containing pyrazolo[3, 4-b]quinoline chromophore

Wan, Wen,Wang, Huibin,Lin, Hong,Wang, Jing,Jiang, Yuansong,Jiang, Haizhen,Zhu, Shizheng,Wang, Zixing,Hao, Jian

, p. 138 - 146 (2015/06/08)

Abstract Organic dyes containing trifluoromethylated-pyrazolo[3, 4-b]quinoline were synthesized by using condensation reaction between substituted pyrazolo-4-formaldehyde and aryl amines in moderate yields. Quantum calculation, electrochemical, photophysi

Microwave assisted friedlander condensation catalyzed by clay

Sabitha, Gowravaram,Satheesh Babu,Subba Reddy,Yadav

, p. 4403 - 4408 (2007/10/03)

Clay catalyzed Friedlander condensation of 2-amino arylaldehyde or ketone with carbonyl compounds containing α-methylene group has been achieved in solvent free condition under microwave irradiation to give polycyclic quinoline derivatives.

Attempted Niementowski condensation of anthranilic acid and its ester with 3-Methyl-1-phenylpyrazolin-5-one

Danel,Tomasik,Kappe,Gheath

, p. 302 - 309 (2007/10/03)

Two groups of compounds were formed in the attempted reaction of anthranilic acid and its ester with 3-methyl-1-phenylpyrazolin -5-one. The reactions of 3-methyl-1-phenylpyrazolin-5-one with aniline generated by decarboxylation of anthranilic acid constituted the first group of products. The second group of products comprised of pyrazole derivatives formed mainly by dimerization and dehydration of two molecules of 3-methyl-1-phenylpyrazolin-5-one.

Condensation of 2-Nitrobenzaldehyde with Pyrazolin-5-ones. Structure of 4-(2'-Nitrobenzylidene)pyrazolin-5-ones and their Reductive Cyclization

Danel, A.,Tomasik, P.

, p. 1013 - 1017 (2007/10/02)

The condensation of 1-H-3-methyl-, 3-methyl-1-phenyl-, 1,3-diphenyl- and 1-methyl-3-phenyl-pyrazolin-5-ones with 2-nitrobenzaldehyde resulted in forming the corresponding 4-(2'-nitrobenzylidene)pyrazolin-5-ones.In some cases these products were assisted b

QUANTUM CHEMICAL CI-1 ANALYSIS OF UV ABSORPTION SPECTRA OF 1H-PYRAZOLOQUINOLINE SYSTEM

Pietrzycki, Wladyslaw,Danel, Andrzej,Tomasik, Piotr

, p. 725 - 742 (2007/10/02)

Simulations of UV-absorption spectra in the region of 200 to 360 nm of 1-methyl-3-phenyl, 1-phenyl-3-methyl- and 1,3-diphenyl-pyrazolo quinolines were carried out.The simulations involved CNDO/S-CI-1 calculations of energies, oscillator strengths a

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