89434-89-9Relevant academic research and scientific papers
Supramolecular architectures in dihydropyridones: Synthesis, crystal structure, Hirshfeld analysis, cytotoxicity and in silico studies
Dowarah, Jayanta,Lalhruaizela,Marak, Brilliant N.,Patel, Devanshi,Singh, Ved Prakash,Sran, Balkaran Singh,Yadav, Umesh Chand Singh
, (2021/10/19)
In this study, a series of five non-aromatic dihydropyridones were synthesized, crystallized, and single-crystal X-ray diffraction was used to obtain their molecular geometries. The supramolecular assembly of the molecules through non-covalent interaction
Chem-grafted Zn-SSA as an Efficient Heterogeneous Catalyst to Synthesize 2-Pyridinones
Zhang, Li Jun,Zhang, Xiang,You, Zhen Sheng,Li, Heng,Feng, Tian,Wang, Wei Li
, p. 2081 - 2086 (2016/10/18)
Abstract: Chemo-selectivity is always a hard problem in preparing 2-pyridinones. Silica sulfuric acid (SSA) modified with zinc chloride (Zn–SSA) was found to be a high efficient heterogeneous catalyst to solve this problem. Under Zn–SSA and solvent-free conditions, the one-pot cyclocondensation of 1,3-dicarbonyl compounds, malononitrile and arylaldehydes to afford 2-pyridinones was conveniently implemented. The heterogeneous reaction was much efficient and promising in pharmaceutical study and industrial production. Graphical Abstract: Improving chemo-selectivity is always a hard problem in preparing 2-pyridinones. Silica sulfuric acid (SSA) modified with zinc chloride (Zn–SSA) was found to be efficient heterogeneous catalyst to solve this problem. Under Zn-SSA and solvent-free conditions, the one-pot cyclocondensation of 1,3-dicarbonyl compounds, malononitrile and arylaldehydes to afford 2-pyridinones was conveniently implemented. The heterogeneous reaction was much efficient and promising in pharmaceutical study and industrial production.[Figure not available: see fulltext.]
Nano crystalline ZnO catalyzed one pot multicomponent reaction for an easy access of fully decorated 4H-pyran scaffolds and its rearrangement to 2-pyridone nucleus in aqueous media
Bhattacharyya, Pranabes,Pradhan, Koyel,Paul, Sanjay,Das, Asish R.
supporting information; experimental part, p. 4687 - 4691 (2012/09/05)
A green and highly efficient protocol has been developed for the synthesis of 4H-pyran scaffolds installing a one-pot three-component coupling reaction of an aldehyde, malononitrile, and a 1,3-diketo compound using nano structured ZnO as the catalyst in a
Synthesis of 3,4-dihydropyridin-2-one derivatives in convergent mode applying bio catalyst vitamin B1 and polymer supported catalyst PEG-SO3H from two different sets of building blocks
Pradhan, Koyel,Bhattacharyya, Pranabes,Paul, Sanjay,Das, Asish R.
, p. 5840 - 5844,5 (2020/08/20)
Two highly efficient, green protocols have been developed for the synthesis of 3,4-dihydropyridin-2-one derivatives from different starting materials exploring two reaction specific catalysts, vitamin B1 (VB 1), and PEG-SO3/sub
ZnO nanoparticles: An efficient reagent, simple and one-pot procedure for synthesis of highly functionalized dihydropyridine derivatives
Khazaei, Marziyeh,Anary-Abbasinejad, Mohammad,Hassanabadi, Alireza,Sadeghi, Bahareh
experimental part, p. 615 - 620 (2012/07/17)
A new and efficient one-pot synthesis of dihydropyridones derivatives by four-component reaction between cyanoacetamide, aryl aldehydes, and ethyl acetoacetate with ammonium acetate using nano ZnO is described. The reaction was performed in ethanol under reflux conditions and afforded good yields of products.
A Facile Preparation of Alkylpyridines from Aminopyrans
Marugan, Monica M.,Martin, Nazario,Seoane, Carlos,Soto, Jose L.
, p. 145 - 150 (2007/10/02)
Alkyl-substituted pyridinones 4, pyrones 5, dihydropyridinones 2, and pyridines 6 are prepared by means of ring transformation of alkyl-substituted 2-amino-4H-purans 1.Some open-chain intermediates (3) as well as the aromatization of the partially unsatur
SYNTHESIS AND STRUCTURE OF SUBSTITUTED 3,4-DIHYDROPYRIDIN-2-ONES
Krauze, A. A.,Liepin'sh, E. E.,Kalme, Z. A.,Pelcher, Yu. E.,Dubur, G. Ya.
, p. 1241 - 1245 (2007/10/02)
The condensation of benzylideneacetoacetic ester with cyanoacetamide in the presence of triethylamine yielded 3-carbamoyl-3,4-dihydropyridin-2-one, while the condensation of arylidenecyanoacetamides with β-aminocrotonic ester in acetic acid yielded 3-cyano-3,4-dihydropyridin-2-ones.It was established by NMR spectroscopy that 3-cyano-4-R-5-ethoxycarbonyl-6-methyl-3,4-dihydropyridin-2-ones exist in solutions in the form of a mixture of cis- and trans-stereosiomers in a 10:1 ratio.
