89523-63-7

Basic information

• Product Name: Zinc, chloro(phenylmethyl)-
• CAS NO: 89523-63-7
• Molecular Formula: C7H7ClZn
• Molecular Weight: 191.976
• Mol File: 89523-63-7.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Zinc, chloro(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Zinc, chloro(phenylmethyl)-(89523-63-7)
• EPA Substance Registry System: Zinc, chloro(phenylmethyl)-(89523-63-7)

Safety Data

• Hazardous Substances Data: 89523-63-7(Hazardous Substances Data)

Upstream product

• 6921-34-2 benzylmagnesium chloride 
• 100-44-7 benzyl chloride 
• 7440-66-6 zinc 
• 7646-85-7 zinc(II) chloride 

Downstream Products

• 886-65-7 trans,trans-1,4-Diphenyl-1,3-butadiene 
• 872051-25-7 1-β-(4-benzylphenyl)-1,2-dideoxy-3,5-di-O-(4-toluoyl)-D-ribofuranose 
• 24265-92-7 (E)-1-(4-benzyloxyphenyl)-2-phenylethene 
• 19566-74-6 (E)-2,6-dimethoxy-4-(phenylethenyl)phenol 
• 1485-70-7 N-benzylbenzamide 
• 942120-28-7 1-(5-bromopyridin-3-yl)-2-phenylethan-1-one 
• 949526-11-8 9-[2,5-bis-O-(tert-butyldimethylsilyl)-3-deoxy-β-D-ribofuranosyl]-6-benzylpurine 
• 108-88-3 toluene 
• 939039-26-6 1-(5-chloropyridin-2-yl)-1-(3-fluoro-5-(trifluoromethyl)phenyl)-2-phenylethanamine 
• 2431-96-1 N,N-diethylphenylacetamide 
• 1415929-56-4 N-[(3,4,5-trifluoro-2,6-dibenzylphenyl)methylene]-4-methylaniline 
• 831-81-2 4-chlorophenyl(phenyl)methane 
• 23450-30-8 methyl 4-benzylbenzoate 
• 1498-71-1 9-benzylanthracene 

Relevant articles and documents

Asymmetric Synthesis of Fluorinated Allenes by Rhodium-Catalyzed Enantioselective Alkylation/Defluorination of Propargyl Difluorides with Alkylzincs

The reaction of propargyl difluorides R1CF2C≡CR2 with alkylzincs R3ZnCl giving axially chiral fluorinated allenes R1FC=C=CR2R3 with high enantioselectivity (up to 99 % ee) was found to be catalyzed by a chiral diene/rhodium complex. A key step in the catalytic cycle is selective elimination of one of the enantiotopic fluorides at the β-position of an alkenyl-Rh intermediate, which is generated by regioselective addition of R3-Rh onto the triple bond of the starting difluorides.

Identification of inhibitors of the immunosuppressive enzyme IL4I1

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Modular Functionalization of Arenes in a Triply Selective Sequence: Rapid C(sp2) and C(sp3) Coupling of C?Br, C?OTf, and C?Cl Bonds Enabled by a Single Palladium(I) Dimer

Full control over multiple competing coupling sites would enable straightforward access to densely functionalized compound libraries. Historically, the site selection in Pd0-catalyzed functionalizations of poly(pseudo)halogenated arenes has been unpredictable, being dependent on the employed catalyst, the reaction conditions, and the substrate itself. Building on our previous report of C?Br-selective functionalization in the presence of C?OTf and C?Cl bonds, we herein complete the sequence and demonstrate the first general arylations and alkylations of C?OTf bonds (in I dimer. This allowed the realization of the first general and triply selective sequential C?C coupling (in 2D and 3D space) of C?Br followed by C?OTf and then C?Cl bonds.