89536-86-7 Usage
Uses
Used in Pharmaceutical Industry:
D-Leucine, N-methyl-, phenylmethyl ester is used as a building block for the synthesis of peptides and pharmaceuticals, due to its unique chemical properties and potential applications in the development of new drugs.
Used in Weight Management and Metabolic Disorder Treatments:
D-Leucine, N-methyl-, phenylmethyl ester is used as an inhibitor of lipid metabolism, which may help in the development of treatments for weight management and metabolic disorders by regulating lipid metabolism and potentially improving metabolic health.
Used in Cancer Research and Treatment Development:
D-Leucine, N-methyl-, phenylmethyl ester is used as a potential inhibitor of cancer cell growth and proliferation, making it a candidate for further research and development in the field of cancer treatment. Its potential role in inhibiting cancer cell growth may lead to the development of new therapeutic strategies for various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 89536-86-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,5,3 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 89536-86:
(7*8)+(6*9)+(5*5)+(4*3)+(3*6)+(2*8)+(1*6)=187
187 % 10 = 7
So 89536-86-7 is a valid CAS Registry Number.
89536-86-7Relevant academic research and scientific papers
Structure-activity relationships of side-chain modified didemnins
Ding, Xiaobin,Vera, Matthew D.,Liang, Bo,Zhao, Yuming,Leonard, Michael S.,Joullie, Madeleine M.
, p. 231 - 234 (2007/10/03)
The synthesis and antitumor activity of a novel didemnin B analogue containing a ψ[CH2NH] amide bond surrogate between N-Me-D-Leu7 and Pro8 are reported. The analogue shows activity (GI50 = 4 nM) comparable to that of didemnin B (GI50 = 13 nM) in the NCI-60 tumor cell screen. This result, along with new data from previously reported synthetic didemnin analogues, is discussed within the context of the side-chain SAR for didemnins.
