89536-86-7 Usage
General Description
D-Leucine, N-methyl-, phenylmethyl ester, also known as N-Methyl-D-Leucine phenylmethyl ester, is a chemical compound classified as a derivative of the amino acid leucine. It is commonly used as a building block in the synthesis of peptides and pharmaceuticals. D-Leucine, N-methyl-, phenylmethyl ester has been identified as an inhibitor of lipid metabolism, potentially making it useful in the development of weight management and metabolic disorder treatments. Additionally, it has been studied for its potential role in inhibiting cancer cell growth and proliferation. However, further research is needed to fully understand the biological activities and potential applications of D-Leucine, N-methyl-, phenylmethyl ester.
Check Digit Verification of cas no
The CAS Registry Mumber 89536-86-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,5,3 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 89536-86:
(7*8)+(6*9)+(5*5)+(4*3)+(3*6)+(2*8)+(1*6)=187
187 % 10 = 7
So 89536-86-7 is a valid CAS Registry Number.
89536-86-7Relevant articles and documents
Structure-activity relationships of side-chain modified didemnins
Ding, Xiaobin,Vera, Matthew D.,Liang, Bo,Zhao, Yuming,Leonard, Michael S.,Joullie, Madeleine M.
, p. 231 - 234 (2007/10/03)
The synthesis and antitumor activity of a novel didemnin B analogue containing a ψ[CH2NH] amide bond surrogate between N-Me-D-Leu7 and Pro8 are reported. The analogue shows activity (GI50 = 4 nM) comparable to that of didemnin B (GI50 = 13 nM) in the NCI-60 tumor cell screen. This result, along with new data from previously reported synthetic didemnin analogues, is discussed within the context of the side-chain SAR for didemnins.
