89691-63-4

Basic information

• Product Name: (R)-(+)-1-(3-methoxyphenyl)-1-ethanol
• CAS NO: 89691-63-4
• Molecular Weight: 152.193
• Mol File: 89691-63-4.mol
• Article Data: 382

Chemical Properties

• CAS DataBase Reference: (R)-(+)-1-(3-methoxyphenyl)-1-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-1-(3-methoxyphenyl)-1-ethanol(89691-63-4)
• EPA Substance Registry System: (R)-(+)-1-(3-methoxyphenyl)-1-ethanol(89691-63-4)

Safety Data

• Hazardous Substances Data: 89691-63-4(Hazardous Substances Data)

Upstream product

• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 75-89-8 2,2,2-trifluoroethanol 
• 58114-05-9 1-chloro-1-(3'-methoxyphenyl)ethane 
• 107-19-7 propargyl alcohol 
• 89691-63-4 1-(3-methoxy)-phenylethanol 
• 123-62-6 propionic acid anhydride 
• 544-97-8 dimethyl zinc(II) 
• 591-31-1 3-methoxy-benzaldehyde 
• 137203-34-0 bis(trimethylaluminum)–1,4-diazabicyclo[2.2.2]octane adduct 
• 917-54-4 methyllithium 
• 97-72-3 2-Methylpropionic anhydride 
• 557-20-0 diethylzinc 
• 1379610-58-8 2-(1-(3-methoxyphenyl)ethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1620164-36-4 rac-1-(3-methoxyphenyl)ethyl sulfate 

Downstream Products

• 58114-05-9 1-chloro-1-(3'-methoxyphenyl)ethane 
• 129052-92-2 N,N-dimethyl-α-(m-methoxyphenyl)ethylamine 
• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 23308-82-9 S-(-)-1-(3-methoxyphenyl)ethanol 
• 23308-82-9 (R)-(+)-1-(3-methoxyphenyl)-1-ethanol 
• 605-55-0 phenanthren-2-ol 
• 13837-48-4 2-methoxyphenanthrene 
• 5329-90-8 2-hydroxy-9,10-dihydrophenanthrene 
• 365515-83-9 N-[1-(3-Methoxyphenyl)ethyl]phthalimide 

Relevant articles and documents

Nickel-Catalyzed Enantioselective Hydroboration of Vinylarenes

The enantioselective hydroboration of vinylarenes catalyzed by a chiral, nonracemic nickel catalyst is presented as a facile method for generating chiral benzylic boronate esters. Various vinylarenes react with bis(pinacolato)diboron (B2pin2) in the presence of MeOH as a hydride source to form chiral boronate esters in up to 92% yield with up to 94% ee. The use of anhydrous Me4NF to activate B2pin2 is crucial for ensuring fast transmetalation to achieve high enantioselectivities.

Mechanochemical, Water-Assisted Asymmetric Transfer Hydrogenation of Ketones Using Ruthenium Catalyst

Asymmetric catalytic reactions are among the most convenient and environmentally benign methods to obtain optically pure compounds. The aim of this study was to develop a green system for the asymmetric transfer hydrogenation of ketones, applying chiral Ru catalyst in aqueous media and mechanochemical energy transmission. Using a ball mill we have optimized the milling parameters in the transfer hydrogenation of acetophenone followed by reduction of various substituted derivatives. The scope of the method was extended to carbo- and heterocyclic ketones. The scale-up of the developed system was successful, the optically enriched alcohols could be obtained in high yields. The developed mechanochemical system provides TOFs up to 168 h?1. Our present study is the first in which mechanochemically activated enantioselective transfer hydrogenations were carried out, thus, may be a useful guide for the practical synthesis of optically pure chiral secondary alcohols.

Visible-Light-Driven Catalytic Deracemization of Secondary Alcohols

Deracemization of racemic chiral compounds is an attractive approach in asymmetric synthesis, but its development has been hindered by energetic and kinetic challenges. Here we describe a catalytic deracemization method for secondary benzylic alcohols which are important synthetic intermediates and end products for many industries. Driven by visible light only, this method is based on sequential photochemical dehydrogenation followed by enantioselective thermal hydrogenation. The combination of a heterogeneous dehydrogenation photocatalyst and a chiral molecular hydrogenation catalyst is essential to ensure two distinct pathways for the forward and reverse reactions. These reactions convert a large number of racemic aryl alkyl alcohols into their enantiomerically enriched forms in good yields and enantioselectivities.