89791-76-4

Usage

Uses

Used in Organic Synthesis:
2-Amino-3-nitro-4,6-dimethyl-5-bromopyridine is used as an intermediate in organic synthesis for the production of various pharmaceuticals and agrochemicals. Its unique structure and reactivity make it a valuable building block for the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, 2-Amino-3-nitro-4,6-dimethyl-5-bromopyridine is used as a key intermediate in the development of new drugs. Its versatile functional groups allow for further chemical modifications and the creation of novel therapeutic agents.
Used in Material Science:
2-Amino-3-nitro-4,6-dimethyl-5-bromopyridine is also used in the development of new materials due to its unique structure and reactivity. Its properties can be exploited to create innovative materials with potential applications in various industries.

Upstream product

• 5407-87-4 2-Amino-4,6-dimethylpyridine 
• 89856-44-0 2-amino-5-bromo-4,6-dimethylpyridine 

Downstream Products

• 50850-16-3 2,3-diamino-4,6-dimethylpyridine 
• 133240-06-9 5,7-dimethyl-2-ethyl-3H-imidazo[4,5-b]pyridine 
• 145004-89-3 3-<<2'-aminosulfonyl><1,1'-biphenyl-4-yl>-methyl>-5,7-dimethyl-2-ethyl-imidazo<4,5-b>pyridine 
• 145004-87-1 5,7-Dimethyl-2-ethyl-3-[(2'-ethoxycarbonylamino sulfonylbiphenyl-4-yl)methyl]-3H-imidazo[4,5-b]pyridine 
• 92336-10-2 6-bromo-5,7-dimethyl-1⁽³⁾H-imidazo[4,5-b]pyridine 
• 116599-55-4 5,7-dimethyl-1(3)H-imidazo[4,5-b]pyridine 
• 121655-34-3 6-bromo-5,7-dimethyl-1H-[1,2,3]triazolo[4,5-b]pyridine 
• 114163-51-8 5,7-dimethyl-1H-[1,2,3]triazolo[4,5-b]pyridine 

Relevant academic research and scientific papers

SOMATOSTATIN MODULATORS AND USES THEREOF

Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.

First demonstration of positive allosteric-like modulation at the human wild type translocator protein (TSPO)

We show that changing the number and position of nitrogen atoms in the heteroatomic core of a pyrazolopyrimidine acetamide is sufficient to induce complex binding to wild type human TSPO. Only compounds with this complex binding profile lacked intrinsic effect on glioblastoma proliferation but positively modulated the antiproliferative effects of a synthetic TSPO ligand. To the best of our knowledge this is the first demonstration of allosteric-like interaction at the wild type human TSPO.

Syntheses of two potential food mutagens

The syntheses of the potential heterocyclic amine food mutagens 1,4,6-trimethyl-2-aminoimidazo[4,5-c]pyridine and 1,5,7-trimethyl-2 -aminoimidazo [4,5-b]pyridine are described.

N-pyridinyl(alkyl)polyhalogenobenzamides acting as TNF-α production inhibitors

A series of N-pyridinyl(methyl)fluorobenzamides issued from 2,4-dimethyl-6-aminopyridine and 3-aminomethylpyridine were synthesized and evaluated as inhibitors of TNF-α production. Although less active than the corresponding phthalimides, several pentaflu

PYRIDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF

Substituted pyridyl imidazole derivatives of formula (I) inhibit effectively the action of angiotensin II and have a superior anti-hypertensive activity. STR1

3N-Methylbiphenylsulfonylurea and -carbamate substituted imidazo[4,5-b]pyridines. Potent antagonists of the ANG II AT1 receptors

The synthesis and the SAR study of imidazo[4,5-b]pyridine biphenyl sulfonylureas and -carbamates as highly potent AT1-seIective ANG II receptor antagonists are described. Several members of this new class of antagonists efficiently inhibited the ANG II-induced presser response in pithed rats after iv and intraduodenal (id) administration.