90056-91-0Relevant academic research and scientific papers
Synthesis of modified pyrimidine bases and positive impact of chemically reactive substituents on their in vitro antiproliferative activity
Noll, Steffi,Kralj, Marijeta,Suman, Lidija,Stephan, Holger,Piantanida, Ivo
body text, p. 1172 - 1179 (2009/09/30)
The antiproliferative activity screening on human tumor cell lines of a series of modified uracil and cytosine bases as well as some corresponding acyclonucleosides, and comparison of structure-activity relationship revealed the importance of chemical rea
Efficient Synthesis of Acyclic Nucleosides by N-Alkylation of Pyrimidine and Purine-bases Using a New Coupling Agent of Cesium Iodide
Kim, Yong Hae,Kim, Joong Young,Lee, Chun Ho
, p. 1045 - 1048 (2007/10/02)
Acyclic nucleosides, ((1,3-bis(benzyloxy)-2-propoxy) methyl)-2-thio-pyrimidine, -uracil, -2-thiouracil, and -2-thioadenine, and (2-acetoxyethoxy methyl)-2-thioadenine, -2-thiopyrimidine, -uracil, and -2-thiouracil have been successfully synthesized in goo
Uracil analogues of the acylonucleoside 9--methyl>guanine (BIOLF-62)
Ogilvie, Kelvin K.,Hamilton, Raymond G.,Gillen, Michael F.,Radatus, Bruno K.,Smith, Kendall O.,Galloway, Karen S.
, p. 16 - 21 (2007/10/02)
A series of substituted uracil analogues of the antiviral agent 9-methyl>guanine (BIOL-62) has been synthesized and characterized.The uracil analogues show little activity against herpesviruses.
