901773-70-4Relevant academic research and scientific papers
Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease
Abás, Sònia,Rodríguez-Arévalo, Sergio,Bagán, Andrea,Gri?án-Ferré, Christian,Vasilopoulou, Foteini,Brocos-Mosquera, Iria,Muguruza, Carolina,Pérez, Belén,Molins, Elies,Luque, F. Javier,Pérez-Lozano, Pilar,De Jonghe, Steven,Daelemans, Dirk,Naesens, Lieve,Brea, José,Loza, M. Isabel,Hernández-Hernández, Elena,García-Sevilla, Jesús A.,García-Fuster, M. Julia,Radan, Milica,Djikic, Teodora,Nikolic, Katarina,Pallàs, Mercè,Callado, Luis F.,Escolano, Carmen
supporting information, p. 3610 - 3633 (2020/04/30)
Imidazoline I2 receptors (I2-IR), widely distributed in the CNS and altered in patients that suffer from neurodegenerative disorders, are orphans from a structural point of view, and new I2-IR ligands are urgently required
Synthesis of isocyanide derivatives of α-aminoalkylphosphonate diphenyl esters
Sieńczyk, Marcin,Kliszczak, Maciej,Oleksyszyn, Józef
, p. 4209 - 4211 (2007/10/03)
This letter describes the first example of the synthesis of isocyanide derivatives of α-aminoalkylphosphonate diphenyl esters. This method produces the title compounds in high purity and in very good yields. It also permits the generation of an α-aminopho
