905575-65-7Relevant articles and documents
Efforts toward elucidating Thalidomide's molecular target: An expedient synthesis of the first Thalidomide biotin analogue
Stewart, Scott G.,Braun, Carlos J.,Polomska, Marta E.,Karimi, Mahdad,Abraham, Lawrence J.,Stubbs, Keith A.
, p. 4059 - 4062 (2010)
Herein we describe the synthesis of the first Thalidomide-biotin analogue in order to initiate investigations into the unknown molecular mode of action of Thalidomide. In this manner we describe the attachment of biotin tether through the Huisgen 1,3-dipo