90788-35-5

Basic information

• Product Name: 3-AMINO-3-(4-METHOXYPHENYL)-2-PROPENOIC ACID ETHYL ESTER
• Synonyms: 3-AMINO-3-(4-METHOXYPHENYL)-2-PROPENOIC ACID ETHYL ESTER
• CAS NO: 90788-35-5
• Molecular Formula: C₁₂H₁₅NO₃
• Molecular Weight: 221.255
• Mol File: 90788-35-5.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-AMINO-3-(4-METHOXYPHENYL)-2-PROPENOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-3-(4-METHOXYPHENYL)-2-PROPENOIC ACID ETHYL ESTER(90788-35-5)
• EPA Substance Registry System: 3-AMINO-3-(4-METHOXYPHENYL)-2-PROPENOIC ACID ETHYL ESTER(90788-35-5)

Safety Data

• Hazardous Substances Data: 90788-35-5(Hazardous Substances Data)

Upstream product

• 2881-83-6 ethyl 4-methoxybenzoylacetate 
• 105-36-2 ethyl bromoacetate 
• 874-90-8 4-methoxybenzonitrile 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 100-07-2 4-methoxy-benzoyl chloride 
• 6148-64-7 ethyl potassium malonate 

Downstream Products

• 161196-78-7 5-methoxy-2-(4-methoxyphenyl)-4-methylnicotinic acid ethyl ester 
• 844439-42-5 ethyl (Z)-3-acetamido-3-(4-methoxyphenyl)propenoate 
• 66092-10-2 diethyl 2,5-bis(4-methoxyphenyl)-1H-pyrrole-3,4-dicarboxylate 
• 1615240-42-0 ethyl 2-(4-methoxyphenyl)-6-phenylnicotinate 
• 187679-23-8 ethyl 2-(4-methoxyphenyl)quinoline-3-carboxylate 
• 199587-26-3 5-(4-Methoxy-phenyl)-2-methyl-1,2-dihydro-pyrazol-3-one 
• 956325-21-6 ethyl 2-(4-methoxy)phenyl-4-methyl-3-pyridinecarboxylate 

Relevant articles and documents

Trifluoroethanol as a Unique Additive for the Chemoselective Electrooxidation of Enamines to Access Unsymmetrically Substituted NH-Pyrroles

An electrochemical method for the synthesis of unsymmetrically substituted NH-pyrroles is described. The synthetic strategy comprises a challenging heterocoupling between two structurally diverse enamines via sequential chemoselective oxidation, addition,

Regioselective Synthesis of N2-Aryl 1,2,3-Triazoles via Electro-oxidative Coupling of Enamines and Aryldiazonium Salts

An efficient synthetic route for the construction of N2-aryl 1,2,3-triazoles is reported via sequential C-N bond formation and electro-oxidative N-N coupling under metal-free conditions. Readily accessible 2-aminoacrylates and aryldiazonium salts were used as starting materials, and the developed protocol displays excellent functional group tolerance, allowing an extensive range of substrate scope up to 91% isolated yield. Various mechanistic studies, along with the isolation of an intermediate adduct, refer to successive ionic and radical reaction sequences.

Divergent Synthesis of Multisubstituted Unsymmetric Pyrroles and Pyrrolin-4-ones from Enamino Esters via Copper-Catalyzed Aerobic Dimerization

A facile synthetic method to access multisubstituted unsymmetric pyrrole and pyrrolin-4-one derivatives is disclosed. In the presence of Cu(OAc)2 and KOAc, substituted pyrrole derivatives are produced in good yields (up to 93 %) through oxidative cyclization of enamino esters. Meanwhile, using CuCl2 and TFA (trifluoroacetic acid), pyrrolin-4-one derivatives are obtained in excellent yields (up to 94 %) through 1,2-aryl migration. A wide range of functional groups have been tolerated, and a reliable method for the synthesis of valuable multisubstituted pyrroles and pyrrolin-4-ones has been developed.