907997-09-5

Upstream product

• 907997-19-7 2-phenyl-1,4-pentadien-3-ol 
• 98-81-7 1-bromovinylbenzene 
• 98-86-2 acetophenone 
• 76886-55-0 Acetophenone 2,4,6-triisopropylbenzenesulphonyl hydrazone 
• 20047-25-0 4-Phenyl-(E)-3-penten-1-ol 
• 55177-38-3 1-[(1E)-1-methyl-1,3-butadienyl]benzene 

Downstream Products

• 1215036-17-1 rac-1-benzyl-4-(hydroxyimino)-3-phenylpiperidine 
• 446302-83-6 1-N-benzyl-3-phenyl-4-piperidone 

Relevant academic research and scientific papers

Synthesis of 3-aryl-substituted tetrahydropyran-4-ones and tetrahydrothiopyran-4-ones

A series of tetrahydropyran-4-one and tetrahydrothiopyran-4-one derivatives with 3-aryl or 3,6-diaryl substituents were prepared by double conjugate addition of water or H2S to divinyl ketones. These starting materials were accessed in two step

Direct Synthesis of Enones by Visible-Light-Promoted Oxygenation of Trisubstituted Olefins Using Molecular Oxygen

A one-step synthesis of enones from olefins is described. The reaction was performed under visible-light irradiation in the presence of molecular oxygen and a photocatalyst. The reaction proceeded with various types of trisubstituted olefins to give enones in good yields with high regioselectivity. In particular, oxygen- and nitrogen-containing functional groups, heteroaromatic rings, and cyclopropanes were tolerated. Mechanistic studies and previous reports indicated that the active oxygen species generated in the reaction system is singlet oxygen.

Development of κ opioid receptor agonists by focusing on phenyl substituents of 4-dimethylamino-3-phenylpiperidine derivatives: Structure-activity relationship study of matrine type alkaloids

A series of new κ opioid receptor (KOR) agonists were developed from the lead compound 4-dimethylamino-1-pentanoylpiperidine (3), a matrine-type alkaloid. Derivatives of 3 were synthesized with a variety of phenyl substituents and evaluated for their anti

Synthesis of 3-phenyl-4-piperidones from acetophenone by shapiro and azamichael reactions and their further derivatization

The Shapiro reaction of acetophenone is the key in a convenient three-step access to a divinyl ketone which is further transformed by double aza-Michael reactions with primary amines into N-substituted 3-phenyl-4-piperidones. In the case of N-benzyl and N

Synthesis of tetrahydropyran-4-ones and thiopyran-4-ones from donor-substituted α-bromostyrene derivatives

Tetrahydropyran-4-one and tetrahydrothiopyran-4-one derivatives with a 3-aryl substituent were synthesized by double-conjugate addition of water or H2S to divinyl ketones. These starting materials were prepared in two steps by conversion of lit