91028-47-6

Upstream product

• 108-22-5 Isopropenyl acetate 
• 186759-45-5 (+/-)-(1-hydroxymethallyl)carbamic acid benzyl ester 
• 91028-46-5 (2S)-2-but-3-en-1-ol 
• 75-36-5 acetyl chloride 
• 142953-04-6 L-2-<(benzyloxycarbonyl)amino>-4-(methylsulphinyl)butan-1-ol 
• 31139-36-3 dibenzyl dicarbonate 
• 108-24-7 acetic anhydride 

Downstream Products

• 142952-98-5 L-2-<(benzyloxycarbonyl)amino>-4-phenylbut-3-enyl acetate 
• 91028-67-0 Acetic acid (R)-2-(3-benzenesulfonyl-4,5-dihydro-isoxazol-5-yl)-2-benzyloxycarbonylamino-ethyl ester 
• 142952-93-0 (2S,3E)-2--4-(1'-cyclohexen-1'-yl)but-3-en-1-yl acetate 
• 142952-99-6 L-2-<(benzyloxycarbonyl)amino>-4-(2-naphthyl)but-3-enyl acetate 
• 142952-97-4 L-2-<(benzyloxycarbonyl)amino>-4-(3-O-methylestr-16-en-17-yl)but-3-enyl acetate 
• 142952-96-3 L-2-<(benzyloxycarbonyl)amino>-4-(cholesta-3,5-dien-3-yl)but-3-enyl acetate 
• 142952-95-2 L-2-<(benzyloxycarbonyl)amino>-4-(3β-acetyloxyepiandrost-16-en-17-yl)but-3-enyl acetate 
• 142953-00-2 L-2-<(benzyloxycarbonyl)amino>-4-(2-ethoxycarbonyl-3-naphthyl)but-3-enyl acetate 
• 142952-94-1 L-2-<(benzyloxycarbonyl)amino>-4-(17β-acetyloxyandrost-2-en-3-yl)but-3-enyl acetate 
• 91028-46-5 (2S)-2-but-3-en-1-ol 
• 271260-80-1 (S)-3-(benzyloxycarbonyl)-2,2-dimethyl-4-vinyloxazolidine 
• 142952-92-9 (S)-4-((E)-2-Cyclohex-1-enyl-vinyl)-oxazolidin-2-one 
• 800391-51-9 acetic acid 4-(5-amino-2,2-dimethyl-4-oxo-chroman-6-yl)-2-benzyloxycarbonylamino-but-3-enyl ester 

Relevant academic research and scientific papers

SYNTHESIS OF CHROMANONES

Processes for the preparation of biologically active chromanones are disclosed, including processes for the preparation of intermediates useful in the preparation of the biologically active chromanones. The chromanones and the intermediates disclosed herein may be useful for a variety of therapies, including the treatment of various cancers and the treatment of inflammation and inflammation related disorders.

Synthesis of unnatural amino acids via suzuki cross-coupling of enantiopure vinyloxazolidine derivatives

(R and S)-α-Amino alcohols and α-amino acids, including 4-methoxyhomophenylalanine, with a variety of unnatural side chains have been synthesized via palladium-catalyzed cross-coupling Suzuki reactions. The key building blocks 1 and 2, synthesized from the common achiral precursor 2-butene-1,4-diol, were made enantiopure utilizing a Pseudomonas cepacia lipase-catalyzed kinetic resolution. The optimal conditions for the Suzuki cross-coupling and the subsequent oxidations of the resultant α-amino alcohols are described.

Heck couplings of non-activated alkenes

The Heck couplings of protected 2-aminobut-3-en-1-ols with cyclohexenyl triflate can be readily carried out using a 'ligand-free' palladium catalyst, potassium carbonate and tetrabutylammonium triflate.

Palladium-catalyzed heck couplings of L-vinylglycine derivatives with vinyl and aryl halides and triflates

The coupling of aryl and vinyl halides and triflates with L-vinylglycine derivatives under the influence of a palladium catalyst is described. The coupling is regioselective and stereoselective with the absolute configuration of the α-amino acid centre be

BENZENESULFONYLCARBONITRILE OXIDE. 5. FACE SELECTIVITY OF CYCLOADDITION TO CHIRAL TERMINAL ALKENES

The diastereomer ratio for cycloaddition of benzenesulfonylcarbonitrile oxide (BSNO) to a series of (S)-vinylglycine-derived alkenes varied from 30:70 to 66:34 depending on the substituents at the chiral center.Isomer ratios were routinely determined by (