910548-26-4 Usage
Uses
Used in Pharmaceutical Industry:
(3R)-N-(tert-Butyloxycarbonyl)-3-Methyl-L-glutaMic Acid is used as a key intermediate in the synthesis of (2S,3R)-3-Me glutamate residue of nonribosomal lipopeptides for their potential therapeutic applications. Nonribosomal lipopeptides are a class of bioactive molecules with diverse biological activities, including antimicrobial, antifungal, and antiviral properties. The incorporation of this chiral amino acid derivative allows for the precise control of the peptide's stereochemistry, which is crucial for their biological activity and selectivity.
Used in Chemical Synthesis:
(3R)-N-(tert-Butyloxycarbonyl)-3-Methyl-L-glutaMic Acid is used as a building block in the chemical synthesis of complex organic molecules, particularly those with chiral centers. The presence of the Boc protecting group allows for selective deprotection and subsequent reactions, enabling the synthesis of a wide range of chiral compounds with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 910548-26-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,0,5,4 and 8 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 910548-26:
(8*9)+(7*1)+(6*0)+(5*5)+(4*4)+(3*8)+(2*2)+(1*6)=154
154 % 10 = 4
So 910548-26-4 is a valid CAS Registry Number.
910548-26-4Relevant academic research and scientific papers
Biosynthesis of the (2S,3R)-3-methyl glutamate residue of nonribosomal lipopeptides
Milne, Claire,Powell, Amanda,Jim, John,Al Nakeeb, Majid,Smith, Colin P.,Micklefield, Jason
, p. 11250 - 11259 (2007/10/03)
The calcium-dependent antibiotics (CDAs) and daptomycin are therapeutically relevant nonribosomal lipopeptide antibiotics that contain penultimate C-terminal 3-methyl glutamate (3-MeGlu) residues. Comparison with synthetic standards showed that (2S,3R)-co
