910548-24-2 Usage
Uses
Used in Pharmaceutical Industry:
(2S,3R)-N-(tert-Butyloxycarbonyl)-3-Methyl-pyroglutaMinol is used as a key intermediate in the preparation of (2S,3R)-3-Me glutamate residue of nonribosomal lipopeptides. These lipopeptides have potential applications in various therapeutic areas, including antibiotics, immunosuppressants, and antifungal agents, due to their unique structural features and biological activities.
In the synthesis of nonribosomal lipopeptides, the (2S,3R)-N-(tert-Butyloxycarbonyl)-3-Methyl-pyroglutaMinol serves as a building block, providing the necessary chiral information and functional groups for the formation of the desired peptide backbone. The Boc protecting group is crucial for preventing unwanted side reactions during the synthesis process, ensuring the correct formation of the peptide bond and the integrity of the final product.
Overall, (2S,3R)-N-(tert-Butyloxycarbonyl)-3-Methyl-pyroglutaMinol is a valuable compound in the field of medicinal chemistry, contributing to the development of novel and effective therapeutic agents with potential applications in various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 910548-24-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,0,5,4 and 8 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 910548-24:
(8*9)+(7*1)+(6*0)+(5*5)+(4*4)+(3*8)+(2*2)+(1*4)=152
152 % 10 = 2
So 910548-24-2 is a valid CAS Registry Number.
910548-24-2Relevant academic research and scientific papers
Biosynthesis of the (2S,3R)-3-methyl glutamate residue of nonribosomal lipopeptides
Milne, Claire,Powell, Amanda,Jim, John,Al Nakeeb, Majid,Smith, Colin P.,Micklefield, Jason
, p. 11250 - 11259 (2007/10/03)
The calcium-dependent antibiotics (CDAs) and daptomycin are therapeutically relevant nonribosomal lipopeptide antibiotics that contain penultimate C-terminal 3-methyl glutamate (3-MeGlu) residues. Comparison with synthetic standards showed that (2S,3R)-co
