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(2S,3R)-N-(tert-Butyloxycarbonyl)-3-Methyl-5-oxo-pyrrolidinecarboxylic Acid is a chiral compound with a specific stereochemistry, featuring a 2S,3R configuration. It is a derivative of pyrrolidinecarboxylic acid, with a tert-butyloxycarbonyl (Boc) protecting group and a 3-methyl substituent. (2S,3R)-N-(tert-Butyloxycarbonyl)-3-Methyl-5-oxo-pyrrolidinecarboxylic Acid is characterized by its 5-oxo functionality, which contributes to its reactivity and potential applications in organic synthesis.

910548-25-3

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910548-25-3 Usage

Uses

Used in Pharmaceutical Industry:
(2S,3R)-N-(tert-Butyloxycarbonyl)-3-Methyl-5-oxo-pyrrolidinecarboxylic Acid is used as a key intermediate in the synthesis of nonribosomal lipopeptides. These lipopeptides are bioactive molecules with potential applications in medicine, particularly as antimicrobial, antifungal, and immunosuppressive agents. (2S,3R)-N-(tert-Butyloxycarbonyl)-3-Methyl-5-oxo-pyrrolidinecarboxylic Acid's unique structure and reactivity enable the preparation of (2S,3R)-3-Me glutamate residues, which are crucial components of these bioactive peptides.

Check Digit Verification of cas no

The CAS Registry Mumber 910548-25-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,0,5,4 and 8 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 910548-25:
(8*9)+(7*1)+(6*0)+(5*5)+(4*4)+(3*8)+(2*2)+(1*5)=153
153 % 10 = 3
So 910548-25-3 is a valid CAS Registry Number.

910548-25-3Relevant academic research and scientific papers

Biosynthesis of the (2S,3R)-3-methyl glutamate residue of nonribosomal lipopeptides

Milne, Claire,Powell, Amanda,Jim, John,Al Nakeeb, Majid,Smith, Colin P.,Micklefield, Jason

, p. 11250 - 11259 (2007/10/03)

The calcium-dependent antibiotics (CDAs) and daptomycin are therapeutically relevant nonribosomal lipopeptide antibiotics that contain penultimate C-terminal 3-methyl glutamate (3-MeGlu) residues. Comparison with synthetic standards showed that (2S,3R)-co

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