91061-36-8Relevant academic research and scientific papers
As neuroprotective agents of pharmaceutical compounds
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Paragraph 0761; 0762; 0765; 0766, (2019/06/26)
The invention discloses a medicinal compound as a neuroprotective agent. The medicinal compound is a neuronal nitric oxide synthase-postsynaptic density protein 95 (nNOS-PSD95) decoupling agent. The medicinal compound is a benzene ring derivative shown in the general formula (I) or its pharmaceutically acceptable salt. The invention further discloses a preparation method of the medicinal compound and a use of the medicinal compound in prevention and treatment on neuronal damage influence-caused diseases.
Directed ortho Metallation Studies on Podocarpic Acid Derivatives: Advantageous Use of a LICKOR Base
Cambie, Richard C.,Higgs, Paul I.,Lee, Kee Chee,Metzler, Michael R.,Rutledge, Peter S.,at al.
, p. 1465 - 1477 (2007/10/02)
Methyl 13-(N,N-diethylcarbamoyl)-12-methoxypodocarpa-8,11,13-trien-19-oate (2), 13-(N,N-diethylcarbamoyl)-12,19-dimethoxypodocarpa-8,11,13-triene (8) and N,N-diethyl-2-methoxy-4,5-dimethylbenzamide (15) were prepared for studies involving lithiation directed ortho to the tertiary amide group, in which the use of a LICKOR base was advantageous.Some dynamic features of the n.m.r. spectra of the amides are discussed.Oxazoline derivatives of both the monocyclic and diterpenoid compounds were synthesized.
